Mitogen-activated protein kinase 9 (Q6881891)

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mammalian protein found in Homo sapiens

mitogen-activated protein kinase 9
c-Jun kinase 2
MAPK9
MAP kinase 9
MAPK 9
stress-activated protein kinase JNK2
SAPK1a
stress-activated protein kinase 1a
Jun kinase
c-Jun N-terminal kinase 2
JNK-55

Language	Label	Description	Also known as
English	Mitogen-activated protein kinase 9	mammalian protein found in Homo sapiens	mitogen-activated protein kinase 9 c-Jun kinase 2 MAPK9 MAP kinase 9 MAPK 9 stress-activated protein kinase JNK2 SAPK1a stress-activated protein kinase 1a Jun kinase c-Jun N-terminal kinase 2 JNK-55

Statements

1 reference

13 November 2019

UniProt protein ID

mitogen-activated protein (MAP) kinase, JNK

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P45984

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P45984

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Mitogen-activated protein (MAP) kinase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

protein serine/threonine kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

protein binding

determination method

10 references

8 April 2019

Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

Role of the ATFa/JNK2 complex in Jun activation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

New insights into the catalytic activation of the MAPK phosphatase PAC-1 induced by its substrate MAPK ERK2 binding

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

8 April 2019

An empirical framework for binary interactome mapping

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

determination method

2 references

transcription factor binding

determination method

1 reference

8 April 2019

Role of the ATFa/JNK2 complex in Jun activation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

JUN kinase activity

determination method

1 reference

8 April 2019

Selective interaction of JNK protein kinase isoforms with transcription factors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

protein serine/threonine/tyrosine kinase activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

MAP kinase activity

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

determination method

3 references

neuron projection

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

biological process

response to cadmium ion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

phosphorylation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

rhythmic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

positive regulation of apoptotic signaling pathway

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

positive regulation of podosome assembly

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

Fc-epsilon receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

protein phosphorylation

determination method

positive regulation of macrophage derived foam cell differentiation

determination method

1 reference

8 April 2019

Ionizing radiation induces macrophage foam cell formation and aggregation through JNK-dependent activation of CD36 scavenger receptors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

positive regulation of gene expression

determination method

1 reference

8 April 2019

Ionizing radiation induces macrophage foam cell formation and aggregation through JNK-dependent activation of CD36 scavenger receptors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

JUN phosphorylation

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

response to mechanical stimulus

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

positive regulation of apoptotic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

neuron development

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

cellular response to organic substance

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

protein localization to tricellular tight junction

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

cellular response to reactive oxygen species

determination method

1 reference

8 April 2019

Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

cellular response to cadmium ion

determination method

1 reference

8 April 2019

Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

positive regulation of protein ubiquitination

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

positive regulation of transcription factor catabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

regulation of gene expression

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

intracellular signal transduction

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

regulation of DNA-binding transcription factor activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45984

determination method

physically interacts with

pyrazolanthrone

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

Gene Atlas image

PBB GE MAPK9 203218 at fs.png
732 × 530; 12 KB

0 references

serine/threonine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P45984

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P45984

mitogen-activated protein (MAP) kinase, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P45984

Identifiers

MeSH descriptor ID

subject named as

Mitogen-Activated Protein Kinase 9

0 references

D08.811.913.696.620.682.700.567.374.750

0 references

D12.776.476.563.567.374.750

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000345524

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000345524

ENSP00000377028

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377028

ENSP00000389338

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000389338

ENSP00000394560

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394560

ENSP00000397422

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397422

ENSP00000321410

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000321410

ENSP00000377029

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377029

ENSP00000380262

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000380262

ENSP00000430608

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000430608

ENSP00000443149

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000443149

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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