Cation-exchange high-performance liquid chromatography assay for the nigrostriatal toxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its monoamine oxidase B generated metabolites in brain tissues (Q68829400)

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scientific article published on 01 July 1987

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English	Cation-exchange high-performance liquid chromatography assay for the nigrostriatal toxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its monoamine oxidase B generated metabolites in brain tissues	scientific article published on 01 July 1987

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scholarly article

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27 September 2019

Cation-exchange high-performance liquid chromatography assay for the nigrostriatal toxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its monoamine oxidase B generated metabolites in brain tissues (English)

1 reference

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27 September 2019

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based on heuristic

inferred from title

high-performance liquid chromatography

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based on heuristic

inferred from title

author name string

T Shinka

1

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27 September 2019

N Castagnoli

2

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27 September 2019

E Y Wu

3

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27 September 2019

M K Hoag

4

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27 September 2019

A J Trevor

5

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publication date

1 July 1987

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27 September 2019

398

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27 September 2019

279-287

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27 September 2019

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 reference

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7 January 2021

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

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Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

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Pargyline Prevents MPTP-Induced Parkinsonism in Primates

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1-Methyl-4-phenylpyridinium ion (MPP+): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra

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7 January 2021

Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes.

1 reference

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7 January 2021

Quantification of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion in brain tissue by gas chromatography/mass spectrometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9673%2801%2996513-6

7 January 2021

HPLC-assay with electrochemical detection for the neurotoxin MPTP, its metabolite MPP+ and MPTP-analogues in biological samples after purification over Sephadex G10.

1 reference

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7 January 2021

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.

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7 January 2021

Metabolism of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by liver homogenate fractions

1 reference

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7 January 2021

Interactions of the 1-methyl-4-phenyl-2,3-dihydropyridinium species with synthetic dopamine-melanin

1 reference

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7 January 2021

Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain

1 reference

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7 January 2021

Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects.

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7 January 2021

Identifiers

10.1016/S0021-9673(01)96513-6

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3498735%20AND%20SRC:MED&resulttype=core&format=json

27 September 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3498735%20AND%20SRC:MED&resulttype=core&format=json

27 September 2019

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