Insulin receptors: structure and function (Q68889503)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

review article

1 reference

title

Insulin receptors: structure and function (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

author name string

E Van Obberghen

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

S Gammeltoft

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

publication date

1 July 1986

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

volume

42

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

issue

7

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28 September 2019

page(s)

727-734

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

28 September 2019

cites work

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12 December 2020

Tyrosine-specific protein kinase activity is associated with the purified insulin receptor

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12 December 2020

Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action

1 reference

12 December 2020

Dephosphorylation of the hepatic insulin receptor: absence of intrinsic phosphatase activity in purified receptors

1 reference

12 December 2020

Insulin receptor: evidence that it is a protein kinase

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12 December 2020

Purification of insulin receptor with full binding activity

1 reference

12 December 2020

Insulin receptor: structure and function

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12 December 2020

Characterization of insulin-mediated phosphorylation of the insulin receptor in a cell-free system

1 reference

12 December 2020

Phosphorylation of insulin receptors solubilized from rat skeletal muscle

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12 December 2020

Regulation of insulin receptor kinase activity by insulin mimickers and an insulin antagonist

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12 December 2020

Kinetic properties and sites of autophosphorylation of the partially purified insulin receptor from hepatoma cells

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12 December 2020

Insulin stimulates phosphorylation of serine residues in soluble insulin receptors

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12 December 2020

Nucleotide sequence of avian sarcoma virus UR2 and comparison of its transforming gene with other members of the tyrosine protein kinase oncogene family

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12 December 2020

New Perspectives on the Mechanism of Insulin Action

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12 December 2020

Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes

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12 December 2020

Interaction of cross-linking agents with the insulin effector system of isolated fat cells. Covalent linkage of 125I-insulin to a plasma membrane receptor protein of 140,000 daltons

1 reference

12 December 2020

Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta

1 reference

12 December 2020

Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice.

1 reference

12 December 2020

A unique proteolytic cleavage site on the beta subunit of the insulin receptor

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12 December 2020

Insulin Receptor Phosphorylation May Not Be a Prerequisite for Acute Insulin Action

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12 December 2020

Decreased autophosphorylation of the insulin receptor-kinase in streptozotocin-diabetic rats.

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12 December 2020

Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity

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12 December 2020

Insulin receptor: covalent labeling and identification of subunits

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12 December 2020

src kinase catalyzes the phosphorylation and activation of the insulin receptor kinase.

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12 December 2020

Purification and properties of insulin receptors from rat liver membranes

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12 December 2020

Insulin-stimulated phosphorylation of the insulin receptor precursor

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12 December 2020

Tyrosine Kinase Activity of the Insulin Receptor of Patients with Type A Extreme Insulin Resistance: Studies with Circulating Mononuclear Cells and Cultured Lymphocytes

1 reference

12 December 2020

Insulin binding and insulin-dependent phosphorylation of the insulin receptor solubilized from human erythrocytes

1 reference

12 December 2020

Insulin stimulated phosphorylation of its own receptor. Activation of a tyrosine-specific protein kinase that is tightly associated with the receptor

1 reference

12 December 2020

The insulin receptor kinase

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12 December 2020

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1 reference

12 December 2020

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1 reference

12 December 2020

Properties of the Insulin Receptor Isolated from Liver and Fat Cell Membranes

1 reference

12 December 2020

Insulin-like effect of vanadate on adipocyte glycogen synthase and on phosphorylation of 95,000 dalton subunit of insulin receptor

1 reference

12 December 2020

Monoclonal antibodies to receptors for insulin and somatomedin-C

1 reference

12 December 2020

Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the M r 95,000 receptor subunit is its own kinase

1 reference

12 December 2020

Phosphorylation activates the insulin receptor tyrosine protein kinase

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12 December 2020

Effects of covalently linked insulin dimers on receptor kinase activity and receptor down regulation

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12 December 2020

Phosphorylation of the hepatic insulin receptor: stimulating effect of insulin on intact cells and in a cell-free system

1 reference

12 December 2020

Defect in Phosphorylation of Insulin Receptors in Cells from an Insulin-Resistant Patient with Normal Insulin Binding

1 reference

12 December 2020

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity

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12 December 2020

A comparison of the insulin- and epidermal growth factor-stimulated protein kinases from human placenta

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12 December 2020

Identification of a cellular 110 000-Da protein substrate for the insulin-receptor kinase

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12 December 2020

Identification of the alpha beta monomer of the adipocyte insulin receptor by insulin binding and autophosphorylation

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12 December 2020

Protein kinase activity of the insulin receptor from muscle

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12 December 2020

Insulin-like effect of trypsin on the phosphorylation of rat adipocyte insulin receptor

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12 December 2020

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor

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12 December 2020

Abnormality of insulin binding and receptor phosphorylation in an insulin-resistant melanoma cell line

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12 December 2020

Identification of functional insulin receptors on membranes from an insulin-producing cell line (RINm5F).

1 reference

12 December 2020

Purification and properties of the human placental insulin receptor.

1 reference

12 December 2020

Direct demonstration of glycosylation of insulin receptor subunits by biosynthetic and external labeling: evidence for heterogeneity

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12 December 2020

Insulin binds to and promotes the phosphorylation of a Mr 210 000 component of its receptor in detergent extracts of rat liver microsomes

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12 December 2020

Phosphorylation and dephosphorylation of the insulin receptor: evidence against an intrinsic phosphatase activity

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12 December 2020

Characterization of the insulin receptor kinase purified from human placental membranes

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12 December 2020

Preferential degradation of the beta subunit of purified insulin receptor. Effect on insulin binding and protein kinase activities of the receptor

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12 December 2020

A partial view of the mechanism of insulin action

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12 December 2020

Growth factors: Mechanism of action and relation to oncogenes

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12 December 2020

Defect in insulin receptor phosphorylation in erythrocytes and fibroblasts associated with severe insulin resistance

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12 December 2020

Human transforming growth factors induce tyrosine phosphorylation of EGF receptors.

1 reference

12 December 2020

Insulin-stimulated tyrosine phosphorylation of the insulin receptor in detergent extracts of human placental membranes. Comparison to epidermal growth factor-stimulated phosphorylation

1 reference

12 December 2020

The insulin receptor: Its structure and function

1 reference

12 December 2020

Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I

1 reference

12 December 2020

The insulin receptor protein kinase. Physicochemical requirements for activity

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12 December 2020

The role of antireceptor antibodies in stimulating phosphorylation of the insulin receptor

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12 December 2020

Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

1 reference

12 December 2020

Photoaffinity labeling of insulin receptor of rat adiopocyte plasma membrane

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12 December 2020

Phosphorylation of exogenous substrates by the insulin receptor-associated protein kinase

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12 December 2020

The insulin receptor of rat brain is coupled to tyrosine kinase activity.

1 reference

12 December 2020

Characteristics of insulin and epidermal growth factor stimulation of receptor autophosphorylation in detergent extracts of rat liver and transplantable rat hepatomas

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12 December 2020

Insulin receptor phosphorylation in intact adipocytes and in a cell-free system

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12 December 2020

The beta subunit of the insulin receptor is an insulin-activated protein kinase

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12 December 2020

Two different protein kinase activities are associated with the insulin receptor

1 reference

12 December 2020

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1 reference

12 December 2020

The role of protein phosphorylation in neural and hormonal control of cellular activity

1 reference

12 December 2020

Insulin Receptors, Receptor Antibodies, and the Mechanism of Insulin Action

1 reference

12 December 2020

Insulin receptors in rat brain: insulin stimulates phosphorylation of its receptor beta-subunit

1 reference

12 December 2020

Cellular oncogenes and retroviruses

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12 December 2020

An endogenous substrate for the insulin receptor-associated tyrosine kinase

1 reference

12 December 2020

Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine

1 reference

12 December 2020

Synthetic peptide substrates for a tyrosine protein kinase

1 reference

12 December 2020

Insulin receptors: binding kinetics and structure-function relationship of insulin

1 reference

12 December 2020

Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.

1 reference

12 December 2020

Insulin-stimulated tyrosine protein kinase. Characterization and relation to the insulin receptor

1 reference

12 December 2020

Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor

1 reference

12 December 2020

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1 reference

12 December 2020

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01941518

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3525209%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

1 reference