Phenotypic and functional analysis of lymphokine-activated killer (LAK) cell clones. Ability of CD3+, LAK cell clones to produce interferon-gamma and tumor necrosis factor upon stimulation with tumor targets (Q69215919)

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scientific article published on 01 January 1989

Language	Label	Description	Also known as
English	Phenotypic and functional analysis of lymphokine-activated killer (LAK) cell clones. Ability of CD3+, LAK cell clones to produce interferon-gamma and tumor necrosis factor upon stimulation with tumor targets	scientific article published on 01 January 1989

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2502310%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

Phenotypic and functional analysis of lymphokine-activated killer (LAK) cell clones. Ability of CD3+, LAK cell clones to produce interferon-gamma and tumor necrosis factor upon stimulation with tumor targets (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2502310%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

author name string

A S Chong

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2502310%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

A Aleksijevic

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2502310%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

P Scuderi

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2502310%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

E M Hersh

4

1 reference

Europe PubMed Central

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30 September 2019

W J Grimes

5

1 reference

Europe PubMed Central

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30 September 2019

publication date

1 January 1989

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Europe PubMed Central

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30 September 2019

Cancer Immunology, Immunotherapy

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2502310%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

29

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2502310%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2502310%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

270-278

1 reference

Europe PubMed Central

PubMed publication ID

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30 September 2019

Surface markers of human lymphokine-activated killer cells and their precursors. Analysis at the population and clonal level

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural killer-sensitive targets stimulate production of TNF-alpha but not TNF-beta (lymphotoxin) by highly purified human peripheral blood large granular lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant interferon-gamma stimulates the production of human tumor necrosis factor in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphokine-activated killer cells. Analysis of progenitors and effectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of asparagine-linked carbohydrate in natural killer cell-mediated cytolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic and functional characterization of recombinant interleukin 2 (rIL 2)-induced activated killer cells: analysis at the population and clonal levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphotoxins, macrophage cytotoxins, and tumor necrosis factors: an interrelated family of antitumor effector molecules.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytostatic and cytotoxic activity of tumor necrosis factor on human cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Status and potential of interleukin-2 for the treatment of neoplastic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphokine-activated killer cells: lysis of fresh syngeneic natural killer-resistant murine tumor cells by lymphocytes cultured in interleukin 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergy of tumor necrosis factor and interleukin 2 in the activation of human cytotoxic lymphocytes: effect of tumor necrosis factor alpha and interleukin 2 in the generation of human lymphokine-activated killer cell cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphokine-activated killer (LAK) cells. Analysis of factors relevant to the immunotherapy of human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human large granular lymphocytes are potent producers of interleukin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking of lymphokine activated killer (LAK) cell mediated cytotoxicity by cell-sized beads bearing tumor cell proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphokine-activated killer cell phenomenon. III. Evidence that IL-2 is sufficient for direct activation of peripheral blood lymphocytes into lymphokine-activated killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation and functional studies of the human lymphokine-activated killer cell.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphokine-activated killer (LAK) cell phenomenon. IV. Lysis by LAK cell clones of fresh human tumor cells from autologous and multiple allogeneic tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human lymphokine-activated killer (LAK) cells: identification of two types of effector cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of multiple cytokines by clones of human large granular lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphokine-activated killer cell activity Characteristics of effector cells and their progenitors in blood and spleen

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 2-activated killer cells: generation in collaboration with interferon gamma and its suppression in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of human NK clones: target specificity and phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human natural lymphocyte effector cells: definition, analysis of activity, and clinical effectiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human lymphokine-activated killer cells: further isolation and characterization of the precursor and effector cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accessory cells, dendritic cells, or monocytes, are required for the lymphokine-activated killer cell induction from resting T cell but not from natural killer cell precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 2-activated human killer cells are derived from phenotypically heterogeneous precursors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell nature of some lymphokine-activated killer (LAK) cells. Frequency analysis of LAK precursors within human T cell populations and clonal analysis of LAK effector cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leu-11+ lymphocytes with natural killer (NK) activity are precursors of recombinant interleukin 2 (rIL 2)-induced activated killer (AK) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-tumor efficacy of lymphokine-activated killer cells and recombinant interleukin 2 in vivo: direct correlation between reduction of established metastases and cytolytic activity of lymphokine-activated killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of activated killer (AK) cells by recombinant interleukin 2 (rIL 2) in collaboration with interferon-gamma (IFN-gamma).

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of interleukin 2, interferon-gamma, and mitogens on the production of tumor necrosis factors alpha and beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prerequisite for the induction of lymphokine-activated killer cells from T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-dose recombinant interleukin 2 in the treatment of patients with disseminated cancer. Responses, treatment-related morbidity, and histologic findings

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma enhances induction of lymphotoxin in recombinant interleukin 2-stimulated peripheral blood mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2502310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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