alpha-Difluoromethylornithine inhibits liver metastasis produced by intrasplenic injection of human tumor cells into nude mice (Q69230512)

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scientific article published on 01 November 1989

Language	Label	Description	Also known as
English	alpha-Difluoromethylornithine inhibits liver metastasis produced by intrasplenic injection of human tumor cells into nude mice	scientific article published on 01 November 1989

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2505959%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

alpha-Difluoromethylornithine inhibits liver metastasis produced by intrasplenic injection of human tumor cells into nude mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2505959%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

liver metastasis

1 reference

based on heuristic

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author name string

K A Zirvi

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2505959%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

K S Dasmahapatra

2

1 reference

Europe PubMed Central

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30 September 2019

U Atabek

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2505959%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

M A Lyons

4

1 reference

Europe PubMed Central

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30 September 2019

publication date

1 November 1989

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Europe PubMed Central

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30 September 2019

Clinical & Experimental Metastasis

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Europe PubMed Central

PubMed publication ID

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30 September 2019

7

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Europe PubMed Central

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30 September 2019

6

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2505959%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

591-598

1 reference

Europe PubMed Central

PubMed publication ID

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30 September 2019

https://scigraph.springernature.com/pub.10.1007/bf01753670

0 references

Polyamine metabolism and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic response of human tumor xenografts in athymic mice to doxorubicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Successful treatment with DL-alpha-difluoromethylornithine in established human small cell variant lung carcinoma implants in athymic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of metastatic Lewis lung carcinoma with DL-alpha-difluoromethylornithine

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamine requirements for induction of HL-60 promyelocyte differentiation by leukocyte-conditioned medium and phorbol ester

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamines in rapid growth and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alpha-difluoromethylornithine on the growth of experimental Wilms' tumor and renal adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An essential role for polyamines in tumor metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of DL-alpha-difluoromethylornithine on the growth and metastasis of B16 melanoma in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of metastatic potential of tumor cells in young nude mice is correlated with low levels of natural killer cell-mediated cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alpha-difluoromethylornithine alone and combined with adriamycin or vindesine on L1210 leukemia in mice, EMT6 solid tumors in mice, and solid tumors induced by injection of hepatoma tissue culture cells in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of polyamine depletion in vivo by DL-alpha-difluoromethylornithine on functionally distinct populations of tumoricidal effector cells in normal and tumor-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suicide enzyme inhibitors as potential drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimetastatic activity of DL-alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of growth of human or hamster pancreatic cancer cell lines by alpha-difluoromethylornithine alone and combined with cis-diamminedichloroplatinum(II).

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of polyamines in the control of cell proliferation and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of polyamine biosynthesis by alpha-difluoromethyl ornithine potentiates the cytotoxic effects of arabinosyl cytosine in HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biology of cancer metastasis and implications for therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-proliferative properties of DL-alpha-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ornithine decarboxylase: essential in proliferation but not differentiation of human promyelocytic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastatic behavior of human tumor cell lines grown in the nude mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamines are necessary for the survival of human small-cell lung carcinoma in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of inhibition of polyamine biosynthesis by DL-alpha-difluoromethylornithine on the growth and melanogenesis of B16 melanoma in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An essential role for polyamine biosynthesis during human granulopoietic differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor Suppression with a Combination of α-Difluoromethyl Ornithine and Interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of EMT6 tumor growth by interference with polyamine biosynthesis; effects of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schedule-dependent interaction of alpha-difluoromethylornithine and cis-diamminedichloroplatinum(II) against human and hamster pancreatic cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/2505959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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