Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (Q69355237)

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scientific article published on 01 May 1989

Language	Label	Description	Also known as
English	Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart	scientific article published on 01 May 1989

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2549430%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart (English)

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30 September 2019

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D Brunkhorst

1

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30 September 2019

H v der Leyen

2

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30 September 2019

W Meyer

3

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30 September 2019

R Nigbur

4

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30 September 2019

C Schmidt-Schumacher

5

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30 September 2019

H Scholz

6

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30 September 2019

publication date

1 May 1989

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30 September 2019

Naunyn-Schmiedeberg's Archives of Pharmacology

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30 September 2019

339

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30 September 2019

5

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30 September 2019

575-583

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30 September 2019

https://scigraph.springernature.com/pub.10.1007/bf00167264

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Comparative cardiovascular effects of three benzimidazole derivatives, AR-L 57 BS, AR-L 100 BS, and AR-L 115 BS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

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Phosphodiesterase-inhibiting properties of newer inotropic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

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A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of several phosphodiesterase-inhibitors on guinea-pig myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

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Usefulness of pimobendan in the treatment of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets. Isolation, characterization, and effects of various reference phosphodiesterase inhibitors and cardiotonic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

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Sensitization of dog and guinea pig heart myofilaments to Ca2+ activation and the inotropic effect of pimobendan: comparison with milrinone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

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UD-CG 115 ? a cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis for the cardiovascular activities of amrinone and AR-L57.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

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New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect on contractility of skinned fibres from mammalian heart and smooth muscle by a new benzimidazole derivative, 4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methy l-3(2H )- pyridazinone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

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The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of some cardiotonic agents on contractility of skinned fibers from mammalian heart.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

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Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

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Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

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Pharmacology of the bipyridines: amrinone and milrinone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

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In search of the digitalis replacement

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

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4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711): a potent inhibitor of adenosine cyclic 3',5'-monophosphate phosphodiesterases in homogenates and tissue slices from rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of milrinone (Corotrope) on the contractility of isolated dog ventricular muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overview of cardiac inotropic mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

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Effects of new inotropic agents on Ca++ sensitivity of contractile proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the cardiotonic effects of AR-L115 and AR-L57: evidence for distinct inotropic mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

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Effects of antiallergic agents, compound 48/80, and some reference inhibitors on the activity of partially purified human lung tissue adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate phosphodiesterases

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the benzimidazole derivatives pimobendan and 2-(4-hydroxy-phenyl)-5-(5-methyl-3-oxo-4,5-dihydro-2H-6- pyridazinyl) benzimidazole . HCl on phosphodiesterase activity and force of contraction in guinea-pig hearts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The positive inotropic response to milrinone in isolated human and guinea pig myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/2549430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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