Neuronal PAS domain protein 2 (Q6955017)

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mammalian protein found in Homo sapiens

member of PAS superfamily 4
bHLHe9
neuronal PAS2
neuronal PAS domain-containing protein 2
member of PAS protein 4
PAS domain-containing protein 4
class E basic helix-loop-helix protein 9
NPAS2
basic-helix-loop-helix-PAS protein MOP4

Language	Label	Description	Also known as
English	Neuronal PAS domain protein 2	mammalian protein found in Homo sapiens	member of PAS superfamily 4 bHLHe9 neuronal PAS2 neuronal PAS domain-containing protein 2 member of PAS protein 4 PAS domain-containing protein 4 class E basic helix-loop-helix protein 9 NPAS2 basic-helix-loop-helix-PAS protein MOP4

Statements

1 reference

13 November 2019

UniProt protein ID

Nuclear translocator

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99743

PAS domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99743

Helix-loop-helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99743

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PAS fold family

1 reference

based on heuristic

inferred from protein domain or family

PAC motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PAS domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

Hsp90 protein binding

determination method

1 reference

8 April 2019

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

protein dimerization activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

protein binding

determination method

1 reference

8 April 2019

Histone acetyltransferase-dependent chromatin remodeling and the vascular clock

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

determination method

3 references

8 April 2019

The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

8 April 2019

Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

determination method

3 references

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

biological process

regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

rhythmic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

positive regulation of DNA repair

determination method

1 reference

8 April 2019

The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

negative regulation of cell death

determination method

1 reference

8 April 2019

The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

circadian regulation of gene expression

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

transcription, DNA-templated

determination method

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99743&geneProductId=UniProtKB:Q99743

determination method

cellular response to DNA damage stimulus

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

response to redox state

determination method

1 reference

8 April 2019

Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

positive regulation of transcription, DNA-templated

determination method

central nervous system development

determination method

1 reference

8 April 2019

Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

circadian rhythm

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

regulation of response to DNA damage stimulus

determination method

1 reference

8 April 2019

The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

regulation of lipid metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

positive regulation of behavioral fear response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99743

determination method

Gene Atlas image

PBB GE NPAS2 39548 at fs.png
732 × 530; 11 KB

0 references

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000338283

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000338283

ENSP00000388528

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000388528

ENSP00000392125

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000392125

ENSP00000393396

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393396

ENSP00000395265

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395265

ENSP00000397595

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397595

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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