The clinical pharmacokinetics of the novel antifolate N10-propargyl-5,8-dideazafolic acid (CB 3717) (Q70106598)

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8 October 2019

title

The clinical pharmacokinetics of the novel antifolate N10-propargyl-5,8-dideazafolic acid (CB 3717) (English)

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8 October 2019

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D L Alison

1

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8 October 2019

D R Newell

2

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8 October 2019

C Sessa

3

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8 October 2019

S J Harland

4

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8 October 2019

L I Hart

5

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8 October 2019

K R Harrap

6

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8 October 2019

A H Calvert

7

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8 October 2019

publication date

1 January 1985

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Cancer Chemotherapy and Pharmacology

8 October 2019

published in

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8 October 2019

volume

14

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8 October 2019

issue

3

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8 October 2019

page(s)

265-271

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Normalization in the fitting of data by iterative methods. Application to tracer kinetics and enzyme kinetics

8 October 2019

cites work

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12 December 2020

Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate

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12 December 2020

7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate

1 reference

12 December 2020

Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-(( 2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino) benzoyl)-L-glutamic acid (CB3717), on human lymphoblastoid cells

1 reference

12 December 2020

Pharmacokinetics of high-dose methotrexate with citrovorum factor rescue

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12 December 2020

Renal clearance of methotrexate in man during high-dose oral and intravenous infusion therapy

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12 December 2020

The nature of experimental error in enzyme kinetic measurments

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12 December 2020

High-dose methotrexate with citrovorum factor rescue and adriamycin in childhood osteogenic sarcoma

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12 December 2020

Some observations on the human pharmacology of methotrexate

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12 December 2020

A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in mice

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12 December 2020

Pharmacokinetics of methotrexate and 7-hydroxymethotrexate following infusions of high-dose methotrexate

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12 December 2020

Assessment of Pharmacokinetic Constants from Postinfusion Blood Curves Obtained after I.V. Infusion

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12 December 2020

High-dose methotrexate with citrovorum factor rescue: predictive value of serum methotrexate concentrations and corrective measures to avert toxicity

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00258131

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8 October 2019

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