Pharmacokinetic-pharmacodynamic analysis of unbound disopyramide directly measured in serial plasma samples in man (Q70418345)

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11 October 2019

title

Pharmacokinetic-pharmacodynamic analysis of unbound disopyramide directly measured in serial plasma samples in man (English)

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11 October 2019

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11 October 2019

author name string

M Thibonnier

1

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11 October 2019

R A Upton

3

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11 October 2019

C D Blume

4

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11 October 2019

R L Williams

5

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11 October 2019

publication date

1 December 1984

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Journal of Pharmacokinetics and Pharmacodynamics

11 October 2019

published in

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11 October 2019

volume

12

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11 October 2019

issue

6

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11 October 2019

page(s)

559-573

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Volume shifts and protein binding estimates using equilibrium dialysis: application to prednisolone binding in humans.

11 October 2019

cites work

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12 December 2020

Role of concentration-dependent plasma protein binding in disopyramide disposition

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12 December 2020

Pharmacokinetics of the antiarrhythmic disopyramide in healthy humans

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12 December 2020

Concentration-dependence of disopyramide binding to plasma protein and its influence on kinetics and dynamics

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12 December 2020

Clinical pharmacokinetics of disopyramide

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12 December 2020

Enzyme immunoassay of disopyramide in serum.

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12 December 2020

Plasma binding of disopyramide

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12 December 2020

Effect of altered disopyramide binding on its pharmacologic response in rabbits

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12 December 2020

The PROPHET system and resource sharing

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12 December 2020

The effects of urine pH and plasma protein binding on the renal clearance of disopyramide

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12 December 2020

The influence of protein binding on disopyramide clearance

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12 December 2020

Quantitative analysis of the disopyramide concentration-effect relationship

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12 December 2020

The problem of choosing weights in nonlinear regression analysis of pharmacokinetic data

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12 December 2020

Effect of disopyramide on left ventricular performance: the relationship of free and total concentrations of the drug and of its mono-N-dealkylated metabolite to noninvasive indices of function

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12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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12 December 2020

Disopyramide serum and pharmacologic effect kinetics applied to the assessment of bioavailability

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12 December 2020

Plasma concentrations and protein binding of disopyramide and mono-N-dealkyldisopyramide during chronic oral disopyramide therapy

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12 December 2020

Determination of unbound fraction of disopyramide in plasma: a comparison of equilibrium dialysis, ultrafiltration through dialysis membranes and ultrafree anticonvulsant drug filters

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12 December 2020

Protein binding and erythrocyte partitioning of disopyramide and its monodealkylated metabolite.

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12 December 2020

The effect of saturable binding to plasma proteins on the pharmacokinetic properties of disopyramide

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12 December 2020

Identifiers

DOI

10.1007/BF01059552

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11 October 2019

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