Doxorubicin and doxorubicinol pharmacokinetics and tissue concentrations following bolus injection and continuous infusion of doxorubicin in the rabbit (Q70633232)

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scientific article published on 01 January 1993

Language	Label	Description	Also known as
English	Doxorubicin and doxorubicinol pharmacokinetics and tissue concentrations following bolus injection and continuous infusion of doxorubicin in the rabbit	scientific article published on 01 January 1993

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scholarly article

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12 October 2019

Doxorubicin and doxorubicinol pharmacokinetics and tissue concentrations following bolus injection and continuous infusion of doxorubicin in the rabbit (English)

1 reference

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12 October 2019

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pharmacokinetics

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based on heuristic

inferred from title

author name string

B J Cusack

1

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12 October 2019

S P Young

2

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12 October 2019

J Driskell

3

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12 October 2019

R D Olson

4

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12 October 2019

publication date

1 January 1993

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12 October 2019

Cancer Chemotherapy and Pharmacology

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12 October 2019

32

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12 October 2019

1

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12 October 2019

53-58

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12 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00685876

0 references

Reduced cardiotoxicity and nephrotoxicity with preservation of antitumor activity of doxorubicin entrapped in stable liposomes in the LOU/M Wsl rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxorubicin cardiotoxicity: analysis of prevailing hypotheses

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous Infusion or Bolus Injection in Cancer Chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of phenytoin on the pharmacokinetics of doxorubicin and doxorubicinol in the rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experience with the use of adriamycin in combination with other anticancer agents using a weekly schedule, with particular reference to lack of cardiac toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adriamycin therapy by continuous intravenous infusion in patients with metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxorubicin Cardiomyopathy: Evaluation by Phonocardiography, Endomyocardial Biopsy, and Cardiac Catheterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological, toxicological, and therapeutic evaluation in mice of doxorubicin entrapped in cardiolipin liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daunorubicin metabolism by rat tissue preparations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced cardiotoxicity of doxorubicin by a 6-hour infusion regimen. A prospective randomized evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prospective randomized comparison of epirubicin and doxorubicin in patients with advanced breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparative study on the antitumor effect, cardiotoxicity and nephrotoxicity of doxorubicin given as a bolus, continuous infusion or entrapped in liposomes in the Lou/M Wsl rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased cardiac toxicity of doxorubicin administered by continuous intravenous infusion in combination chemotherapy for metastatic breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adriamycin metabolism in man. Evidence from urinary metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daunomycin-induced cardiotoxicity in children and adults. A review of 110 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective alterations in rat cardiac mRNA induced by doxorubicin: Possible subcellular mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Might adriamycinol contribute to adriamycin-induced cardiotoxicity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and antitumor activity of 4-demethoxydaunorubicin, 4-demethoxy-7,9-diepidaunorubicin, and their beta anomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetics of doxorubicin given by three different schedules with equal dose intensity in patients with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution and antitumor activity of adriamycin given in a high-dose and a repeated low-dose schedule to mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic study of i.v. infusions of adriamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxorubicin toxicity and pharmacokinetics in old and young rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear binding as a determinant of tissue distribution of adriamycin, daunomycin, adriamycinol, daunorubicinol and actinomycin D

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiomyopathy of Doxorubicin in Experimental Animals. Factors Affecting the Severity, Distribution and Evolution of Myocardial Lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced cardiotoxicity of doxorubicin delivered on a weekly schedule. Assessment by endomyocardial biopsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Weekly doxorubicin versus doxorubicin every 3 weeks in cyclophosphamide, doxorubicin, and cisplatin chemotherapy for non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adriamycin given as a weekly schedule without a loading course: clinically effective with reduced incidence of cardiotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps. A correlative study of cardiac muscle with isolated membrane fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytofluorescence localization and disposition of doxorubicin and doxorubicinol in rat cardiac tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of a low-protein diet on doxorubicin pharmacokinetics in the rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/8462124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00685876

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8462124%20AND%20SRC:MED&resulttype=core&format=json

12 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8462124%20AND%20SRC:MED&resulttype=core&format=json

12 October 2019

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