Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I (Q70915257)

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14 October 2019

title

Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I (English)

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14 October 2019

2

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14 October 2019

Josef Köhrle

8

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14 October 2019

author name string

F Boege

1

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14 October 2019

A Kehr

3

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14 October 2019

C Boesenberg

4

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14 October 2019

K Christiansen

5

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14 October 2019

A Andersen

6

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14 October 2019

F Jakob

7

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14 October 2019

language of work or name

English

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publication date

1 January 1996

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Journal of Biological Chemistry

14 October 2019

published in

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14 October 2019

volume

271

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14 October 2019

issue

4

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14 October 2019

page(s)

2262-2270

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Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands

14 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

The effects of the bioflavonoid quercetin on squamous cell carcinoma of head and neck origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Antiproliferative activity of quercetin on normal bone marrow and leukaemic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

The effect of quercetin on cell cycle progression and growth of human gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Synergistic antiproliferative activity of quercetin and cisplatin on ovarian cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

The combination of quercetin and cytosine arabinoside synergistically inhibits leukemic cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Enhancement of the antiproliferative activity of cis-diamminedichloroplatinum(II) by quercetin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Strand scission in DNA induced by quercetin and Cu(II): role of Cu(I) and oxygen free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Effect of genistein on topoisomerase activity and on the growth of [Val 12]Ha-ras-transformed NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Preferential relaxation of supercoiled DNA containing a hexadecameric recognition sequence for topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

A strategy for identifying novel, mechanistically unique inhibitors of topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Acidic phospholipids directly inhibit DNA binding of mammalian DNA topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Suppression of active oxygen-induced cytotoxicity by flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Protein kinase C inhibition by plant flavonoids. Kinetic mechanisms and structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Crystal structure determination at 2.3-A resolution of human transthyretin-3',5'-dibromo-2',4,4',6-tetrahydroxyaurone complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

DNA topoisomerase poisons as antitumor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

The current status of camptothecin analogues as antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Saintopin, a new antitumor antibiotic with topoisomerase II dependent DNA cleavage activity, from Paecilomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

Antitumor activity of intoplicine (RP 60475, NSC 645008), a new benzo-pyrido-indole: evaluation against solid tumors and leukemias in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.4.2262

21 January 2018

Identifiers

DOI

10.1074/JBC.271.4.2262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8567688%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

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