Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis (Q71660966)

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20 October 2019

title

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis (English)

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20 October 2019

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Crystal RG

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20 October 2019

McElvaney NG

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Rosenfeld MA

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Chu CS

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Mastrangeli A

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Hay JG

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Brody SL

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Jaffe HA

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Eissa NT

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Danel C

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publication date

1 September 1994

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20 October 2019

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volume

8

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issue

1

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20 October 2019

page(s)

42-51

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https://scigraph.springernature.com/pub.10.1038/ng0994-42

20 October 2019

exact match

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cites work

Identification of the cystic fibrosis gene: chromosome walking and jumping

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7 January 2021

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

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Identification of the cystic fibrosis gene: genetic analysis

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Expression and characterization of the cystic fibrosis transmembrane conductance regulator.

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Cystic fibrosis transmembrane conductance regulator: a chloride channel with novel regulation

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Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

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Cystic fibrosis: molecular biology and therapeutic implications

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Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis

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The lung in cystic fibrosis. A quantitative study including prevalence of pathologic findings among different age groups

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In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

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7 January 2021

Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer

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Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

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7 January 2021

The ADA human gene therapy clinical protocol

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Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

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Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo

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7 January 2021

Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer

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7 January 2021

Newly recognized respiratory tract viruses

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7 January 2021

Gene transfer to freshly isolated human respiratory epithelial cells in vitro using a replication-deficient adenovirus containing the human cystic fibrosis transmembrane conductance regulator cDNA.

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Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis

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Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses.

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Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats.

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Lung gene therapy: in vivo adenovirus-mediated gene transfer to rhesus monkey airway epithelium

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Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: biological efficacy study.

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Acute responses of non-human primates to airway delivery of an adenovirus vector containing the human cystic fibrosis transmembrane conductance regulator cDNA.

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7 January 2021

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.

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7 January 2021

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

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Interleukin 6 enhances a cellular activity that functionally substitutes for E1A protein in transactivation

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Etiologic relationship of the RI-67 agent to acute respiratory disease (ARD).

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The virus watch program: a continuing surveillance of viral infections in metropolitan New York families. VI. Observations of adenovirus infections: virus excretion patterns, antibody response, efficiency of surveillance, patterns of infections, and

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Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study

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Cytokines in sputum and serum from patients with cystic fibrosis and chronicpseudomonas aeruginosa infection as markers of destructive inflammation in the lungs

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Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level

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Role of early region 3 (E3) in pathogenesis of adenovirus disease

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7 January 2021

Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis

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7 January 2021

Evaluation of the respiratory epithelium of normals and individuals with cystic fibrosis for the presence of adenovirus E1a sequences relevant to the use of E1a- adenovirus vectors for gene therapy for the respiratory manifestations of cystic fibros

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7 January 2021

Extensive posttranscriptional deletion of the coding sequences for part of nucleotide-binding fold 1 in respiratory epithelial mRNA transcripts of the cystic fibrosis transmembrane conductance regulator gene is not associated with the clinical manif

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7 January 2021

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer

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7 January 2021

Increased bioelectric potential difference across respiratory epithelia in cystic fibrosis

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Maintenance of alveolitis in patients with chronic beryllium disease by beryllium-specific helper T cells

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7 January 2021

Identifiers

DOI

10.1038/NG0994-42

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7527271%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

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