Dissociation of the alphaIIbbeta3-integrin by EGTA stimulates the tyrosine kinase pp72(syk) without inducing platelet activation (Q71742597)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8900125%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

title

Dissociation of the alphaIIbbeta3-integrin by EGTA stimulates the tyrosine kinase pp72(syk) without inducing platelet activation (English)

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20 October 2019

author name string

E V Negrescu

series ordinal

1

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20 October 2019

W Siess

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8900125%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

language of work or name

English

0 references

publication date

1 October 1996

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8900125%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

20 October 2019

published in

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20 October 2019

volume

271

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20 October 2019

issue

43

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20 October 2019

page(s)

26547-26553

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Integrins and signal transduction pathways: the road taken

20 October 2019

cites work

1 reference

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Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb

21 January 2018

1 reference

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Integrin cytoplasmic domains mediate inside-out signal transduction

21 January 2018

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Regulation of protein tyrosine kinases in platelets

21 January 2018

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Regulation of platelet function by the cytoskeleton.

21 January 2018

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Differential regulation of protein-tyrosine phosphatases by integrin alpha IIb beta 3 through cytoskeletal reorganization and tyrosine phosphorylation in human platelets

21 January 2018

1 reference

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Integrin alpha IIb beta 3-mediated translocation of CDC42Hs to the cytoskeleton in stimulated human platelets

21 January 2018

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Identification and function of the high affinity binding sites for Ca2+ on the surface of platelets

21 January 2018

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Ligand and cation binding are dual functions of a discrete segment of the integrin beta 3 subunit: cation displacement is involved in ligand binding

21 January 2018

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Involvement of divalent cations in the complex between the platelet glycoproteins IIb and IIIa

21 January 2018

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Dissociation of the glycoprotein IIb-IIIa complex in isolated human platelet membranes. Dependence of pH divalent cations

21 January 2018

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Effects of EDTA on the membrane glycoproteins IIb-IIIa complex--analysis using flow cytometry

21 January 2018

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Alpha IIb beta 3 integrin dissociation induced by EDTA results in morphological changes of the platelet surface-connected canalicular system with differential location of the two separate subunits

21 January 2018

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Decreased association of 45calcium with platelets unable to aggregate due to thrombasthenia or prolonged calcium deprivation

21 January 2018

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Chelation therapy for intermittent claudication. A double-blind, randomized, controlled trial.

21 January 2018

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Focal adhesion kinase and associated proteins

21 January 2018

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Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets

21 January 2018

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Adhesive ligand binding to integrin alpha IIb beta 3 stimulates tyrosine phosphorylation of novel protein substrates before phosphorylation of pp125FAK

21 January 2018

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Adhesive signaling in platelets

21 January 2018

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Involvement of Protein-Tyrosine Kinase p72syk in Collagen-Induced Signal Transduction in Platelets

21 January 2018

1 reference

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Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor

21 January 2018

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Platelet shape change induced by thrombin receptor activation. Rapid stimulation of tyrosine phosphorylation of novel protein substrates through an integrin- and Ca(2+)-independent mechanism

21 January 2018

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Effects of ethylenediamine tetracetic acid (EDTA) on platelet structure

21 January 2018

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Calcium store depletion in dimethyl BAPTA-loaded human platelets increases protein tyrosine phosphorylation in the absence of a rise in cytosolic calcium

21 January 2018

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Calcium mobilisation controls tyrosine protein phosphorylation independently of the activation of protein kinase C in human platelets

21 January 2018

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Identification of two distinct regions within the binding sites for fibrinogen and fibronectin on the IIb-IIIa human platelet membrane glycoprotein complex by monoclonal antibodies P2 and P4

21 January 2018

1 reference

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Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

21 January 2018

1 reference

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Divalent cation regulation of the surface orientation of platelet membrane glycoprotein IIb. Correlation with fibrinogen binding function and definition of a novel variant of Glanzmann's thrombasthenia

21 January 2018

1 reference

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Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.43.26547

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8900125%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference