Amsacrine-promoted DNA cleavage site determinants for the two human DNA topoisomerase II isoforms alpha and beta (Q71951683)

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22 October 2019

title

Amsacrine-promoted DNA cleavage site determinants for the two human DNA topoisomerase II isoforms alpha and beta (English)

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22 October 2019

6

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22 October 2019

Caroline Austin

8

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22 October 2019

author name string

K L Marsh

1

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22 October 2019

E Willmore

2

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22 October 2019

S Tinelli

3

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22 October 2019

M Cornarotti

4

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22 October 2019

E L Meczes

5

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22 October 2019

L M Fisher

7

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22 October 2019

language of work or name

English

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publication date

1 December 1996

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22 October 2019

published in

Biochemical Pharmacology

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22 October 2019

volume

52

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22 October 2019

issue

11

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22 October 2019

page(s)

1675-1685

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22 October 2019

1 reference

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Recent studies of DNA topoisomerases

7 January 2021

1 reference

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Isolation and characterization of a human cDNA clone encoding a novel DNA topoisomerase II homologue from HeLa cells.

7 January 2021

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Novel HeLa topoisomerase II is the II beta isoform: complete coding sequence and homology with other type II topoisomerases.

7 January 2021

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Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development

7 January 2021

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The 180-kDa isoform of topoisomerase II is localized in the nucleolus and belongs to the structural elements of the nucleolar remnant

7 January 2021

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Localization of DNA topoisomerase II in Chinese hamster fibroblasts by confocal and electron microscopy

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DNA topoisomerases as targets for cancer therapy

7 January 2021

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Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors

7 January 2021

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Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives

7 January 2021

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A consensus sequence for cleavage by vertebrate DNA topoisomerase II.

7 January 2021

1 reference

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Local base sequence preferences for DNA cleavage by mammalian topoisomerase II in the presence of amsacrine or teniposide.

7 January 2021

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Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase II beta

7 January 2021

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Local sequence requirements for DNA cleavage by mammalian topoisomerase II in the presence of doxorubicin.

7 January 2021

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Drosophila topoisomerase II double-strand DNA cleavage: analysis of DNA sequence homology at the cleavage site

7 January 2021

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Base mutation analysis of topoisomerase II-idarubicin-DNA ternary complex formation. Evidence for enzyme subunit cooperativity in DNA cleavage

7 January 2021

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Structure and mechanism of DNA topoisomerase II

7 January 2021

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Mitoxantrone resistance in HL-60 leukemia cells: reduced nuclear topoisomerase II catalytic activity and drug-induced DNA cleavage in association with reduced expression of the topoisomerase II beta isoform

7 January 2021

1 reference

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Cloning and characterization of full-length cDNAs coding for the DNA topoisomerase II beta from Chinese hamster lung cells sensitive and resistant 9-OH-ellipticine

7 January 2021

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10.1016/S0006-2952(96)00516-3

7 January 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8986129%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

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