Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules (Q72271969)

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25 October 2019

title

Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules (English)

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25 October 2019

5

H G Rammensee

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25 October 2019

author name string

K Falk

1

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25 October 2019

O Rötzschke

2

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25 October 2019

S Stevanović

3

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25 October 2019

G Jung

4

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25 October 2019

publication date

1 January 1994

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25 October 2019

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25 October 2019

volume

39

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25 October 2019

issue

4

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25 October 2019

page(s)

230-242

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https://scigraph.springernature.com/pub.10.1007/bf00188785

25 October 2019

exact match

0 references

cites work

Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle

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The set of naturally processed peptides displayed by DR molecules is tuned by polymorphism of residue 86.

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Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition

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Mutations that impair a posttranscriptional step in expression of HLA-A and -B antigens

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Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

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Dipeptidyl Peptidase IV in the Immune System. Effects of Specific Enzyme Inhibitors on Activity of Dipeptidyl Peptidase IV and Proliferation of Human Lymphocytes

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Natural peptide ligand motifs of two HLA molecules associated with myasthenia gravis

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The HLA-A,B "negative" mutant cell line C1R expresses a novel HLA-B35 allele, which also has a point mutation in the translation initiation codon

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12 December 2020

Specificity pockets for the side chains of peptide antigens in HLA-Aw68

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12 December 2020

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

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Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

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Peptides naturally presented by MHC class I molecules

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12 December 2020

Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs

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12 December 2020

Identifiers

DOI

10.1007/BF00188785

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8119729%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

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