The effect of dihydronicotinate N-substitution on the brain-targeting efficacy of a zidovudine chemical delivery system (Q72589635)

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27 October 2019

title

The effect of dihydronicotinate N-substitution on the brain-targeting efficacy of a zidovudine chemical delivery system (English)

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27 October 2019

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M E Brewster

1

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E Pop

2

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27 October 2019

A J Braunstein

3

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A C Pop

4

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P Druzgala

5

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A Dinculescu

6

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W Anderson

7

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A Elkoussi

8

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N Bodor

9

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publication date

1 September 1993

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27 October 2019

published in

Pharmaceutical Research

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volume

10

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issue

9

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27 October 2019

page(s)

1356-1362

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Pharmacokinetics and bioavailability of zidovudine in humans

27 October 2019

cites work

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12 December 2020

Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine

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12 December 2020

Prodrugs and site-specific drug delivery

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12 December 2020

AIDS dementia: synthesis and properties of a derivative of 3'-azido-3'-deoxythymidine (AZT) that may become 'locked' in the central nervous system

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12 December 2020

Synthesis and biological evaluation of prodrugs of zidovudine

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12 December 2020

A pro-drug of zidovudine with enhanced efficacy against human immunodeficiency virus

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12 December 2020

HIV encephalopathy and dementia

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12 December 2020

Improved brain delivery of AZT using a glycosyl phosphotriester prodrug.

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12 December 2020

Ester prodrugs of zidovudine

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12 December 2020

Novel method for determination of partition coefficients of penicillins and cephalosporins by high-pressure liquid chromatography

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12 December 2020

Site-specific, sustained release of drugs to the brain.

1 reference

12 December 2020

Brain, Blood, and Cerebrospinal Fluid Distribution of a Zidovudine Chemical Delivery System in Rabbits

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12 December 2020

Analysis of zidovudine distribution to specific regions in rabbit brain using microdialysis.

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12 December 2020

Prevalence of neuropsychological deficit in HIV infection. Incipient signs of AIDS dementia complex in patients with AIDS.

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12 December 2020

AIDS dementia complex and primary HIV brain infection

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12 December 2020

Hybrid pharmacokinetic models to describe anti-HIV nucleoside brain disposition following parent and prodrug administration in mice.

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12 December 2020

A review of the pharmacokinetics of zidovudine in man.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1018986217181

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27 October 2019

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