Interaction of α2-macroglobulin with trypsin, chymotrypsin, plasmin, and papain (Q72691443)

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28 October 2019

title

Interaction of alpha 2-macroglobulin with trypsin, chymotrypsin, plasmin, and papain (English)

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28 October 2019

Interaction of α2-macroglobulin with trypsin, chymotrypsin, plasmin, and papain (English)

1 reference

https://api.crossref.org/works/10.1016/0003-9861(83)90143-1

24 August 2023

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24 August 2023

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https://api.crossref.org/works/10.1016/0003-9861(83)90143-1

24 August 2023

author name string

J. B. Howell

1

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24 August 2023

T. Beck

2

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24 August 2023

B. Bates

3

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24 August 2023

M. J. Hunter

4

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language of work or name

English

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publication date

1 February 1983

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28 October 2019

15 February 1983

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6187288

full work available at URL

24 August 2023

https://api.elsevier.com/content/article/PII:0003986183901431?httpAccept=text/xml

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https://api.elsevier.com/content/article/PII:0003986183901431?httpAccept=text/plain

24 August 2023

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Archives of Biochemistry and Biophysics

24 August 2023

published in

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28 October 2019

volume

221

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28 October 2019

issue

1

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page(s)

261-270

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Physical and chemical properties of human plasma β2-macroglobulin

28 October 2019

cites work

1

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Studies on human plasma alpha 2-macroglobulin-enzyme interactions. Evidence for proteolytic modification of the subunit chain structure

24 August 2023

2

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The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

24 August 2023

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Degradation of human fibrinogen by plasms alpha2-macroglobulin-enzyme complexes

24 August 2023

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The separation of alpha-2 macroglobulin into five components with differing electrophoretic and enzyme-binding properties

24 August 2023

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Plasma inhibitors of the components of the fibrinolytic pathway in man

24 August 2023

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Plasminogen: Purification from Human Plasma by Affinity Chromatography

24 August 2023

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Activation of human plasminogen by an insoluble derivative of urokinase. Structural changes of plasminogen in the course of activation to plasmin and demonstration of a possible intermediate compound

24 August 2023

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A two-step procedure for purification of papain from extract of papaya latex

24 August 2023

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Affinity chromatography: specific binding of hemoglobin on agarose linked haptoglobin

24 August 2023

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Physical and chemical properties of human plasma β2-macroglobulin

24 August 2023

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p-Nitrophenyl-p'-guanidinobenzoate HCl: a new active site titrant for trypsin

24 August 2023

15

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Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidinobenzoate esters. Titration of the enzymes

24 August 2023

16

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The Determination of the Concentration of Hydrolytic Enzyme Solutions: α-Chymotrypsin, Trypsin, Papain, Elastase, Subtilisin, and Acetylcholinesterase1

24 August 2023

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pK perturbations of nitrophenol-containing reporter groups at the active site of papain

24 August 2023

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Reactions of papain and of low-molecular-weight thiols with some aromatic disulphides. 2,2'-Dipyridyl disulphide as a convenient active-site titrant for papain even in the presence of other thiols

24 August 2023

19

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Alpha 2-macroglobulin-protease reactions: relationship of covalent bond formation, methylamine reactivity, and specific proteolysis

24 August 2023

25

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The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule

24 August 2023

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Further characterization of the covalent linking reaction of α2-macroglobulin

24 August 2023

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A thiol-ester in α2-macroglobulin cleaved during proteinase complex formation

24 August 2023

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Sequence location of the reactive thiol ester in human alpha 2-macroglobulin

24 August 2023

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Primary structure of the 'bait' region for proteinases in alpha 2-macroglobulin. Nature of the complex

24 August 2023

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Trypsin-induced activation of the thiol esters in α2-macroglobulin generates a short-lived intermediate (‘nascent’ α2M) that can react rapidly to incorporate not only methylamine or putrescine but also proteins lacking proteinase activity

24 August 2023

31

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Mechanism of proteinase complex formation with alpha 2-macroglobulin. Three modes of trypsin binding

24 August 2023

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Primary and secondary cleavage sites in the bait region of α2 -macroglobulin

24 August 2023

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Functional modifications of α2-macroglobulin by primary amines. Kinetics of inactivation of α2-macroglobulin by methylamine, and formation of anomalous complexes with trypsin

24 August 2023

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24 August 2023

Identifiers

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28 October 2019

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