Generation and reactivity of "nascent" alpha 2-macroglobulin: localization of cross-links in alpha 2-macroglobulin-trypsin complex (Q72732218)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6202195%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

title

Generation and reactivity of "nascent" alpha 2-macroglobulin: localization of cross-links in alpha 2-macroglobulin-trypsin complex (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6202195%20AND%20SRC:MED&resulttype=core&format=json

history and philosophy of science

28 October 2019

main subject

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

27 August 2023

author name string

L. Sottrup-Jensen

1

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27 August 2023

H. F. Hansen

2

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27 August 2023

U. Christensen

3

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27 August 2023

language of work or name

English

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publication date

1 January 1983

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6202195%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

28 October 2019

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1749-6632.1983.tb18109.x

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1749-6632.1983.tb18109.x/fullpdf

27 August 2023

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Annals of the New York Academy of Sciences

27 August 2023

published in

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28 October 2019

volume

421

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28 October 2019

page(s)

188-208

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The interaction of alpha2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases

28 October 2019

cites work

3

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

MACROGLOBULIN FROM HUMAN PLASMA WHICH FORMS AN ENZYMATICALLY ACTIVE COMPOUND WITH TRYPSIN

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Determination of alpha-2-macroglobulin as trypsin-protein esterase

27 August 2023

5

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Primary structure of the 'bait' region for proteinases in alpha 2-macroglobulin. Nature of the complex

27 August 2023

6

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Proteolytic cleavage sites on α2-macroglobulin resulting in proteinase binding are different for trypsin and staphylococcus aureus V-8 proteinase

27 August 2023

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Primary and secondary cleavage sites in the bait region of α2 -macroglobulin

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8

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

A thiol-ester in α2-macroglobulin cleaved during proteinase complex formation

27 August 2023

9

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester

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10

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Further characterization of the covalent linking reaction of α2-macroglobulin

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11

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Trypsin-induced activation of the thiol esters in α2-macroglobulin generates a short-lived intermediate (‘nascent’ α2M) that can react rapidly to incorporate not only methylamine or putrescine but also proteins lacking proteinase activity

27 August 2023

12

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Mechanism of proteinase complex formation with alpha 2-macroglobulin. Three modes of trypsin binding

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Molecular alteration of alpha-2-macroglobulin by aliphatic amines

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Characterization of alkylamine-sensitive site in alpha 2-macroglobulin

27 August 2023

15

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Nascent alpha 2-macroglobulin-trypsin complex: incorporation of amines and water at the thiol esterified Glx-residues of alpha 2-macroglobulin during activation with trypsin

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17

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Evidence for presence of an internal thiolester bond in third component of human complement.

27 August 2023

18

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Sequence determination of the thiolester site of the fourth component of human complement.

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Covalent binding and hemolytic activity of complement proteins

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20

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

The covalent-binding reaction of complement component C3

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Effect of protease binding by .alpha.2-macroglobulin on intrinsic fluorescence

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Human alpha-2-macroglobulin. Studies on the electrophoretic heterogeneity

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

The separation of alpha-2 macroglobulin into five components with differing electrophoretic and enzyme-binding properties

27 August 2023

31

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule

27 August 2023

32

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Characterization of human plasminogen. II. Separation and partial characterization of different molecular forms of human plasminogen

27 August 2023

33

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Functional modifications of α2-macroglobulin by primary amines. Kinetics of inactivation of α2-macroglobulin by methylamine, and formation of anomalous complexes with trypsin

27 August 2023

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Thiol reduction of human α2-macroglobulin. The subunit structure

27 August 2023

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Sequence location of the reactive thiol ester in human alpha 2-macroglobulin

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Covalent binding of proteinases in their reaction with α2-macroglobulin

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Analysis of amino acid phenylthiohydantoins by high-performance liquid chromatography using gradient elution with ethanol

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43

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

ON THE STRUCTURE AND FUNCTION OF BOVINE TRYPSINOGEN AND TRYPSIN

27 August 2023

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Sequence location of a putative transglutaminase crosslinking site in human α2-macroglobulin

27 August 2023

45

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution.

27 August 2023

46

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https://api.crossref.org/works/10.1111/J.1749-6632.1983.TB18109.X

27 August 2023

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6202195%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

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