Synthesis, binding and structure-affinity studies of new ligands for the microsomal anti-estrogen binding site (AEBS) (Q72995250)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Synthesis, binding and structure-affinity studies of new ligands for the microsomal anti-estrogen binding site (AEBS) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

author name string

M Poirot

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

P De Medina

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

F Delarue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

J J Perie

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

A Klaebe

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

J C Faye

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

language of work or name

English

0 references

publication date

1 August 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

Bioorganic & Medicinal Chemistry

31 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

page(s)

2007-2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

Mechanisms of growth inhibition by nonsteroidal antioestrogens in human breast cancer cells

31 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Variation of the inhibition of calmodulin dependent cyclic AMP phosphodiesterase amongst analogues of tamoxifen; correlations with cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Physicochemical and genetic evidence for specific antiestrogen binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

A diphenylmethane derivative selective for the anti-estrogen binding site may help define its biological role

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Modifications of benzylphenoxy ethanamine antiestrogen molecules: influence affinity for antiestrogen binding site (AEBS) and cell cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Ligands of the antiestrogen binding site block endothelial cell proliferation reversibly

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

The intracellular histamine antagonist, N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethamine.HCL, may potentiate doxorubicin in the treatment of metastatic breast cancer: Results of a pilot study

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine in combination with cyclophosphamide: an active, low-toxicity regimen for metastatic hormonally unresponsive prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Results of a clinical trial in humans with refractory cancer of the intracellular histamine antagonist, N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine-HCl, in combination with various single antineoplastic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Synthesis of 2-(p-chlorobenzyl)-3-aryl-6-methoxybenzofurans as selective ligands for antiestrogen-binding sites. Effects on cell proliferation and cholesterol synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Phase II trial of N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine.HCl and doxorubicin chemotherapy in metastatic breast cancer: A National Cancer Institute of Canada clinical trials group study

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Comparative affinity of steroidal and non-steroidal antioestrogens, cholesterol derivatives and compounds with a dialkylamino side chain for the rat liver antioestrogen binding site.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Antagonism of estrogen receptor and calmodulin association by antiestrogens is not dependent on an interaction with calmodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Structure-activity relationship of antiestrogens. Studies on 2,3-diaryl-1-benzopyrans

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Microsomal epoxide hydrolase of rat liver is a subunit of theanti-oestrogen-binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

Differential Initiation of Translation of a Single Estrogen Receptor mRNA Could Explain Some Estradiol Resistance Cases

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2800%2900119-X

7 January 2021

10.1016/S0968-0896(00)00119-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11003145%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference