Mutations in the primer grip region of HIV reverse transcriptase can increase replication fidelity (Q73019259)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Mutations in the primer grip region of HIV reverse transcriptase can increase replication fidelity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

author name string

M Wisniewski

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

C Palaniappan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Z Fu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

S F Le Grice

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

P Fay

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

R A Bambara

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

language of work or name

English

0 references

publication date

1 October 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

31 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

page(s)

28175-28184

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

Molecular biology: Reverse transcriptase rides again

31 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Fidelity of HIV-1 reverse transcriptase copying RNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Frameshift errors initiated by nucleotide misincorporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Analyzing fidelity of DNA polymerases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Mechanisms of retroviral mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Differences in mutagenesis during minus strand, plus strand and strand transfer (recombination) synthesis of the HIV-1 gene in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

The accuracy of reverse transcriptase from HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Reverse transcriptase fidelity and HIV-1 variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

High rate of mismatch extension during reverse transcription in a single round of retrovirus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Retroviral Recombination and Reverse Transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Misincorporation by HIV-1 reverse transcriptase promotes recombination via strand transfer synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Rate and mechanism of nonhomologous recombination during a single cycle of retroviral replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Structure of HIV-1 reverse transcriptase/DNA complex at 7 A resolution showing active site locations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Alterations to the primer grip of p66 HIV-1 reverse transcriptase and their consequences for template-primer utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Mutating a conserved motif of the HIV-1 reverse transcriptase palm subdomain alters primer utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Mutations within the primer grip region of HIV-1 reverse transcriptase result in loss of RNase H function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Alanine-scanning mutations in the "primer grip" of p66 HIV-1 reverse transcriptase result in selective loss of RNA priming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Kinetic Analysis of Four HIV-1 Reverse Transcriptase Enzymes Mutated in the Primer Grip Region of p66

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Fidelity of mutant HIV-1 reverse transcriptases: interaction with the single-stranded template influences the accuracy of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type 1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Biochemical basis of DNA replication fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Misalignment-mediated DNA synthesis errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

HIV pathogenesis. Lines drawn in epitope wars

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

The fidelity of the reverse transcriptases of human immunodeficiency viruses and murine leukemia virus, exhibited by the mispair extension frequencies, is sequence dependent and enzyme related

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Fidelity of DNA synthesis exhibited in vitro by the reverse transcriptase of the lentivirus equine infectious anemia virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

On the Fidelity of DNA Replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Fidelity of mammalian DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Fidelity of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Mutational specificity of animal cell DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Exonucleolytic proofreading by calf thymus DNA polymerase delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

Fidelity of mammalian DNA replication and replicative DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28175

21 January 2018

Identifiers

DOI

10.1074/JBC.274.40.28175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10497170%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference