Fluorobenzamidrazone thrombin inhibitors: influence of fluorine on enhancing oral absorption (Q73022408)

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31 October 2019

title

Fluorobenzamidrazone thrombin inhibitors: influence of fluorine on enhancing oral absorption (English)

1 reference

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31 October 2019

author name string

K Lee

1

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31 October 2019

W H Jung

2

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31 October 2019

S Y Hwang

3

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31 October 2019

S H Lee

4

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31 October 2019

language of work or name

English

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publication date

1 September 1999

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Bioorganic & Medicinal Chemistry Letters

31 October 2019

published in

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31 October 2019

volume

9

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31 October 2019

issue

17

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31 October 2019

page(s)

2483-2486

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New thrombin inhibitors in cardiovascular disease.

31 October 2019

cites work

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7 January 2021

Challenges in the development of orally bioavailable thrombin active site inhibitors

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Cardiovascular chemotherapy: anticoagulants

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Orally effective CVS-1123 prevents coronary artery thrombosis in the conscious dog.

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7 January 2021

Melagatran, an oral active-site inhibitor of thrombin, prevents or delays formation of electrically induced occlusive thrombus in the canine coronary artery

1 reference

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7 January 2021

Discovery of LB30057, a benzamidrazone-based selective oral thrombin inhibitor

1 reference

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7 January 2021

Structural modification of an orally active thrombin inhibitor, LB30057: replacement of the D-pocket-binding naphthyl moiety.

1 reference

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7 January 2021

Benzylamine-based selective and orally bioavailable inhibitors of thrombin

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7 January 2021

1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors

1 reference

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7 January 2021

Design of novel, potent, noncovalent inhibitors of thrombin with nonbasic P-1 substructures: rapid structure-activity studies by solid-phase synthesis

1 reference

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7 January 2021

Synthesis of a series of potent and orally bioavailable thrombin inhibitors that utilize 3,3-disubstituted propionic acid derivatives in the P3 position

1 reference

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7 January 2021

Potent and efficacious thienylamidine-incorporated thrombin inhibitors

1 reference

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7 January 2021

Thrombin inhibitors based on a propargylglycine template

1 reference

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7 January 2021

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Identifiers

DOI

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31 October 2019

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