FR900482 class of anti-tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo (Q73081564)

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1 November 2019

title

FR900482 class of anti-tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo (English)

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1 November 2019

author name string

L Beckerbauer

1

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1 November 2019

J J Tepe

2

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1 November 2019

J Cullison

3

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1 November 2019

R Reeves

4

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1 November 2019

R M Williams

5

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1 November 2019

publication date

1 October 2000

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1 November 2019

published in

Chemistry and Biology

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1 November 2019

volume

7

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1 November 2019

issue

10

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1 November 2019

page(s)

805-812

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HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1 November 2019

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The gene for the human architectural transcription factor HMGI-C consists of five exons each coding for a distinct functional element

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A poly(dA-dT) upstream activating sequence binds high-mobility group I protein and contributes to lymphotoxin (tumor necrosis factor-beta) gene regulation

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The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta gene

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Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins

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High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters

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Chromosomal translocations in benign tumors: the HMGI proteins

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FR900482, a close cousin of mitomycin C that exploits mitosene-based DNA cross-linking

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7 January 2021

Mitomycin C: small, fast and deadly (but very selective)

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The role of high-mobility group I(Y) proteins in expression of IL-2 and T cell proliferation

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Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction.

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Analysis of chromatin structure by in vivo formaldehyde cross-linking.

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Alu repeats and human disease

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African origin of human-specific polymorphic Alu insertions

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Effect of FK973, a new antitumor antibiotic, on the cell cycle of L1210 cells in vitro

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7 January 2021

A new antitumor antibiotic, FR-900482. IV. Hematological toxicity in mice.

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7 January 2021

10.1016/S1074-5521(00)00028-4

Identifiers

DOI

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1 November 2019

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