N-terminal and core-domain random mutations in human topoisomerase II alpha conferring bisdioxopiperazine resistance (Q73084582)

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1 November 2019

title

N-terminal and core-domain random mutations in human topoisomerase II alpha conferring bisdioxopiperazine resistance (English)

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1 November 2019

2

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1 November 2019

John L. Nitiss

4

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1 November 2019

author name string

L H Jensen

1

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1 November 2019

M Møller

3

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1 November 2019

M Sehested

5

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1 November 2019

P B Jensen

6

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1 November 2019

publication date

1 September 2000

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1 November 2019

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1 November 2019

volume

480

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1 November 2019

issue

2-3

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1 November 2019

page(s)

201-207

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Structure and mechanism of DNA topoisomerase II

1 November 2019

cites work

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Essential mitotic functions of DNA topoisomerase IIalpha are not adopted by topoisomerase IIbeta in human H69 cells

21 January 2018

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DNA topoisomerases: essential enzymes and lethal targets

21 January 2018

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Catalytic inhibitors of DNA topoisomerase II

21 January 2018

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Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

21 January 2018

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Steady-state and rapid kinetic analysis of topoisomerase II trapped as the closed-clamp intermediate by ICRF-193

21 January 2018

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Yeast cells expressing differential levels of human or yeast DNA topoisomerase II: a potent tool for identification and characterization of topoisomerase II-targeting antitumour agents

21 January 2018

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A novel mechanism of cell killing by anti-topoisomerase II bisdioxopiperazines

21 January 2018

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Interaction of the DNA topoisomerase II catalytic inhibitor meso-2,3-bis(3,5-dioxopiperazine-1-yl)butane (ICRF-193), a bisdioxopiperazine derivative, with the conserved region(s) of eukaryotic but not prokaryotic enzyme.

21 January 2018

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Analysis of a core domain in Drosophila DNA topoisomerase II. Targeting of an antitumor agent ICRF-159.

21 January 2018

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Catalysis of ATP hydrolysis by two NH(2)-terminal fragments of yeast DNA topoisomerase II

21 January 2018

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The bis(naphthalimide) DMP-840 causes cytotoxicity by its action against eukaryotic topoisomerase II.

21 January 2018

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Recovery of plasmids from yeast into Escherichia coli: shuttle vectors.

21 January 2018

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A quantitative decatenation assay for type II topoisomerases

21 January 2018

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Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

21 January 2018

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Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalpha

21 January 2018

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The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

21 January 2018

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DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism

21 January 2018

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10.1016/S0014-5793(00)01934-7

21 January 2018

Identifiers

DOI

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1 November 2019

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