Phosphoinositide 3-kinase inhibition reverses platelet aggregation triggered by the combination of the neutrophil proteinases elastase and cathepsin G without impairing alpha(IIb)beta(3) integrin activation (Q73191359)

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scientific article published on 01 November 2000

Language	Label	Description	Also known as
English	Phosphoinositide 3-kinase inhibition reverses platelet aggregation triggered by the combination of the neutrophil proteinases elastase and cathepsin G without impairing alpha(IIb)beta(3) integrin activation	scientific article published on 01 November 2000

Statements

scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Phosphoinositide 3-kinase inhibition reverses platelet aggregation triggered by the combination of the neutrophil proteinases elastase and cathepsin G without impairing alpha(IIb)beta(3) integrin activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

platelet aggregation

1 reference

based on heuristic

inferred from title

Mustapha Si-Tahar

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Dominique Pidard

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

C Trumel

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

V Balloy

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

M Chignard

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

H Chap

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

B Payrastre

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

M Plantavid

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

publication date

1 November 2000

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

484

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

184-188

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

The phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Cathepsin G activates protease-activated receptor-4 in human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Human neutrophil elastase proteolytically activates the platelet integrin alphaIIbbeta3 through cleavage of the carboxyl terminus of the alphaIIb subunit heavy chain. Involvement in the potentiation of platelet aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

A novel integrin-activated pathway forms PKB/Akt-stimulatory phosphatidylinositol 3,4-bisphosphate via phosphatidylinositol 3-phosphate in platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

A type II phosphoinositide 3-kinase is stimulated via activated integrin in platelets. A source of phosphatidylinositol 3-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Reversible translocation of phosphoinositide 3-kinase to the cytoskeleton of ADP-aggregated human platelets occurs independently of Rho A and without synthesis of phosphatidylinositol (3,4)-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

The novel inositol lipid phosphatidylinositol 3,4-bisphosphate is produced by human blood platelets upon thrombin stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Phosphatidylinositol 3,4,5-trisphosphate-dependent stimulation of phospholipase C-gamma2 is an early key event in FcgammaRIIA-mediated activation of human platelets.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2800%2902152-9

21 January 2018

Identifiers

10.1016/S0014-5793(00)02152-9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11078875%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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