Effects of alprazolam, a benzodiazepine, on the ACTH-, GH- and PRL-releasing activity of hexarelin, a synthetic peptidyl GH secretagogue (GHS), in patients with simple obesity and in patients with Cushing's disease (Q73196588)

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scientific article published on 01 November 1999

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English	Effects of alprazolam, a benzodiazepine, on the ACTH-, GH- and PRL-releasing activity of hexarelin, a synthetic peptidyl GH secretagogue (GHS), in patients with simple obesity and in patients with Cushing's disease	scientific article published on 01 November 1999

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11081154%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Effects of alprazolam, a benzodiazepine, on the ACTH-, GH- and PRL-releasing activity of hexarelin, a synthetic peptidyl GH secretagogue (GHS), in patients with simple obesity and in patients with Cushing's disease (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11081154%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Cushing's disease

1 reference

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Roberta Giordano

6

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2 November 2019

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S Grottoli

1

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2 November 2019

E Arvat

2

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2 November 2019

C Gauna

3

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2 November 2019

B Maccagno

4

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2 November 2019

J Ramunni

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2 November 2019

M Maccario

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2 November 2019

R Deghenghi

8

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2 November 2019

E Ghigo

9

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2 November 2019

publication date

1 November 1999

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2 November 2019

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2 November 2019

2

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2 November 2019

3

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2 November 2019

197-204

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2 November 2019

https://scigraph.springernature.com/pub.10.1023/a:1009992909247

0 references

Constitutive growth hormone secretion in sheep after hypothalamopituitary disconnection and the direct in vivo pituitary effect of growth hormone releasing peptide 6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

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Alprazolam blocks the naloxone-stimulated hypothalamo-pituitary-adrenal axis in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

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Effects of dexamethasone and alprazolam, a benzodiazepine, on the stimulatory effect of hexarelin, a synthetic GHRP, on ACTH, cortisol and GH secretion in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of arginine and pyridostigmine on the GHRH-induced GH rise in obesity and Cushing's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone-releasing peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adrenocorticotropin- and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushing's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

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Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

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The growth hormone secretagogue, L-692,429, induces phosphatidylinositol hydrolysis and hormone secretion by human pituitary tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of acipimox, an antilipolytic drug, on the growth hormone (GH) response to GH-releasing hormone alone or combined with arginine in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperactivity of the hypothalamo-pituitary-adrenal axis in obesity: a study of ACTH, AVP, beta-lipotrophin and cortisol responses to insulin-induced hypoglycaemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hypothalamic-pituitary-adrenal axis in obese women with different patterns of body fat distribution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread transcription of the growth hormone-releasing peptide receptor gene in neuroendocrine human tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of growth hormone-releasing activity of hexarelin in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alprazolam on pituitary-adrenal and catecholaminergic responses to metabolic stress in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hexarelin, a synthetic growth-hormone releasing peptide, shows no interaction with corticotropin-releasing hormone and vasopressin on adrenocorticotropin and cortisol secretion in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressants and hypothalamic-pituitary-adrenocortical regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro characterization of four novel classes of growth hormone-releasing peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A receptor in pituitary and hypothalamus that functions in growth hormone release

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does alprazolam, in contrast to diazepam, activate alpha 2-adrenoceptors involved in the regulation of rat growth hormone secretion?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroendocrine and monoaminergic responses to acute administration of alprazolam in normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatotrope responsiveness to Hexarelin, a synthetic hexapeptide, is refractory to the inhibitory effect of glucose in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: evidence for a marked somatotroph secretory capability in obesity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidomimetic regulation of growth hormone secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo effects of the triazolobenzodiazepine alprazolam on hypothalamic-pituitary-adrenal function: pharmacological and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH-releasing stimuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the hypothalamo-pituitary-adrenal axis by the growth hormone (GH) secretagogue, GH-releasing peptide-6, in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of an opiate antagonist on the hormonal changes induced by hexarelin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticotropin-releasing hormone in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of impaired growth hormone secretion in genetically obese Zucker rats: roles of growth hormone-releasing factor and somatostatin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central effects of growth hormone-releasing hexapeptide (GHRP-6) on growth hormone release are inhibited by central somatostatin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hyp

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepines attenuate the pituitary-adrenal responses to corticotrophin-releasing hormone in healthy volunteers, but not in patients with Cushing's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a new G-protein-linked receptor for growth hormone secretagogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a pituitary growth hormone-releasing peptide (GHRP) receptor subtype by photoaffinity labeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the growth hormone secretagogue receptor in pituitary adenomas and other neuroendocrine tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stress-, but not corticotropin-releasing hormone-induced activation of the pituitary-adrenal axis in man is blocked by alprazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone (GH)-releasing peptide stimulation of GH release from human somatotroph adenoma cells: interaction with GH-releasing hormone, thyrotropin-releasing hormone, and octreotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endocrinology of obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GH, prolactin, ACTH and cortisol responses to Hexarelin, a synthetic hexapeptide, undergo different age-related variations

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of GHRP-2 and Hexarelin, Two Synthetic GH-Releasing Peptides, on GH, Prolactin, ACTH and Cortisol Levels in Man. Comparison with the Effects of GHRH, TRH and hCRH

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small peptides as potent releasers of growth hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of growth hormone release after the combined administration of GHRH and GHRP-6 in patients with Cushing's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous alprazolam challenge in normal subjects. Biochemical, cardiovascular, and behavioral effects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acromegaly and Cushing's syndrome due to ectopic production of GHRH and ACTH by a thymic carcinoid tumour: in vitro responses to GHRH and GHRP-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific receptors for synthetic GH secretagogues in the human brain and pituitary gland.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alprazolam attenuates vasopressin-stimulated adrenocorticotropin and cortisol release: evidence for synergy between vasopressin and corticotropin-releasing hormone in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of c-fos messenger ribonucleic acid in neuropeptide Y and growth hormone (GH)-releasing factor neurons in the rat arcuate nucleus following systemic injection of the GH secretagogue, GH-releasing peptide-6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human fetal pituitary expresses functional growth hormone-releasing peptide receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothalamic-pituitary-adrenal axis activity and its relationship to the autonomic nervous system in women with visceral and subcutaneous obesity: effects of the corticotropin-releasing factor/arginine-vasopressin test and of stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidomimetic Regulation of Growth Hormone Secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081154

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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