Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy (Q73199554)

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scientific article published on 01 October 1999

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English	Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy	scientific article published on 01 October 1999

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scholarly article

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2 November 2019

Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy (English)

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2 November 2019

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2 November 2019

author name string

H Löster

1

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2 November 2019

J Grommisch

3

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2 November 2019

W Gründer

4

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publication date

1 October 1999

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2 November 2019

Molecular and Cellular Biochemistry

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1-2

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93-102

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2 November 2019

https://scigraph.springernature.com/pub.10.1023/a:1006966817286

0 references

Stunned myocardium after rapid correction of acidosis. Increased oxygen cost of contractility and the role of the Na(+)-H+ exchange system

1 reference

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Effects of L-propionylcarnitine on mechanical recovery during reflow in intact hearts

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Intracellular high-energy phosphate transfer in normal and hypertrophied myocardium

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Anaplerotic effect of propionyl carnitine in rat heart mitochondria

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Modulation of adenine nucleotide translocase activity during myocardial ischemia

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Effects of ischemia on rat myocardial function and metabolism in diabetes

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Reversible inhibition of adenine nucleotide translocation by long chain acyl-CoA esters in bovine heart mitochondria and inverted submitochondrial particles. Comparison with atractylate and bongkrekic acid

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Effect of ischemia on NMR detection of phosphorylated metabolites in the intact rat heart.

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Effect of propionyl-L-carnitine on mechanical function of isolated rabbit heart

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Paradoxical role of lipid metabolism in heart function and dysfunction

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Regulation of fatty acid beta-oxidation in rat heart mitochondria

1 reference

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Protective effect of propionyl-L-carnitine against ischaemia and reperfusion-damage

1 reference

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Effects of L-carnitine on mechanical recovery of isolated rat hearts in relation to the perfusion with glucose and palmitate

1 reference

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Relationships between carnitine and coenzyme A esters in tissues of normal and alloxan-diabetic sheep

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Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A a

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Protection of the ischemic myocardium by propionylcarnitine taurine amide. Comparison with other carnitine derivatives

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Intracellular pH measurements by phosphorus-31 nuclear magnetic resonance. Influence of factors other than pH on phosphorus-31 chemical shifts

1 reference

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Observation of Mg2+.ATP and uncomplexed ATP in slow exchange by 31P-NMR at high magnetic fields

1 reference

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Salient effects of L-carnitine on adenine-nucleotide loss and coenzyme A acylation in the diabetic heart perfused with excess palmitic acid. A phosphorus-31 NMR and chemical extract study

1 reference

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Anti-ischaemic efficacy of L-propionylcarnitine--a promising novel metabolic approach to ischaemia?

1 reference

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Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/energy cost transfer function

1 reference

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Lack of correlation between the antiarrhythmic effect of L-propionylcarnitine on reoxygenation-induced arrhythmias and its electrophysiological properties

1 reference

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Transport and function of L-carnitine and L-propionylcarnitine: relevance to some cardiomyopathies and cardiac ischemia

1 reference

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In vivo and in vitro intervention with L-carnitine prevents abnormal energy metabolism in isolated diabetic rat heart: chemical and phosphorus-31 NMR evidence

1 reference

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The carnitine acyltransferases and their role in modulating acyl-CoA pools

1 reference

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Metabolic effects of propionate, hexanoate and propionylcarnitine in normoxia, ischaemia and reperfusion. Does an anaplerotic substrate protect the ischaemic myocardium?

1 reference

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12 December 2020

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Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle

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12 December 2020

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Prophylaxis of early ventricular fibrillation by inhibition of acylcarnitine accumulation

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Abnormal phosphocreatine metabolism in perfused diabetic hearts. A 31P nuclear-magnetic-resonance study

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Propionyl-L-carnitine-mediated improvement in contractile function of rat hearts oxidizing acetoacetate

1 reference

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Protection of the ischaemic myocardium by L-propionylcarnitine: effects on the recovery of cardiac output after ischaemia and reperfusion, carnitine transport, and fatty acid oxidation

1 reference

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Changes in tissue levels of carnitine and other metabolites during myocardial ischemia and anoxia

1 reference

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Carnitine in intermediary metabolism. The metabolism of fatty acid esters of carnitine by mitochondria

1 reference

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12 December 2020

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Specificity of carnitine action on fatty acid oxidation by heart muscle

1 reference

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12 December 2020

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Alterations of carbohydrate and lipid metabolism in the acutely ischemic heart

1 reference

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Effect of propionyl-L-carnitine on experimental induced cardiomyopathy in rats

1 reference

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High doses of L-carnitine in acute myocardial infarction: metabolic and antiarrhythmic effects

1 reference

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Carnitine: metabolism and clinical chemistry

1 reference

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Carnitine stimulation of glucose oxidation in the fatty acid perfused isolated working rat heart

1 reference

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Control of oxidative metabolism in volume-overloaded rat hearts: effect of propionyl-L-carnitine

1 reference

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12 December 2020

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Carnitine--metabolism and functions

1 reference

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12 December 2020

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In vivo flux between phosphocreatine and adenosine triphosphate determined by two-dimensional phosphorous NMR.

1 reference

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12 December 2020

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Acyl-CoA inhibition of adenine nucleotide translocation in ischemic myocardium

1 reference

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12 December 2020

based on heuristic

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Fatty acid homeostasis in the normoxic and ischemic heart

1 reference

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12 December 2020

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Bacterial carnitine metabolism

1 reference

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12 December 2020

based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of creatine phosphate from creatine and 32P-labelled ATP by isolated rabbit heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

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Lipid-mediated impairment of normal energy metabolism in the isolated perfused diabetic rat heart studied by phosphorus-31 NMR and chemical extraction

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The propionyl-L-carnitine hypothesis: an alternative approach to treating heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of carnitine in fatty acid metabolism of normal and ischemic myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propionyl-L-carnitine: biochemical significance and possible role in cardiac metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of post-ischemic myocardial metabolism by 1H-magnetic resonance spectroscopy in the rabbit heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic and physiological differences between zero-flow and low-flow myocardial ischemia: effects of L-acetylcarnitine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-propionylcarnitine enhancement of substrate oxidation and mitochondrial respiration in the diabetic rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction rates of creatine kinase and ATP synthesis in the isolated rat heart. A 31P NMR magnetization transfer study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of fatty acid uptake by heart mitochondria: an acylcarnitine-carnitine exchange

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-propionylcarnitine effect on postexercise and postischemic hyperemia in patients affected by peripheral vascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology and biochemistry of pyruvate dehydrogenase complexes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acylcarnitine accumulation does not correlate with reperfusion recovery in palmitate-perfused rat hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relative contribution of glucose and fatty acids to ATP production in hearts reperfused following ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term hemodynamic effects of intravenous propionyl-L-carnitine in anesthetized dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial regulation of phosphocreatine/inorganic phosphate ratios in exercising human muscle: a gated 31P NMR study

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coenzyme A and carnitine distribution in normal and ischemic hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute improvement of cardiac function with intravenous L-propionylcarnitine in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate-induced alterations of high energy phosphate metabolism and contractile function in the perfused heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative importance of pyruvate dehydrogenase interconversion and feed-back inhibition in the effect of fatty acids on pyruvate oxidation by rat heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CARNITINE AND ITS ROLE IN FATTY ACID METABOLISM

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Fatty Acids on Contractility and Rhythm of the Heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of L-carnitine on tissue levels of free fatty acid, acyl CoA, and acylcarnitine in ischemic heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorus nuclear magnetic resonance spectroscopy of cardiac and skeletal muscles

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemodynamic study of intravenous propionyl-L-carnitine in patients with ischemic heart disease and normal left ventricular function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of administration of L-propionylcarnitine during ischemia on the recovery of myocardial function in the anesthetised pig

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-propionylcarnitine effects on cardiac carnitine content and function in secondary carnitine deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The isolated perfused heart according to Langendorff technique--function--application

1 reference

https://pubmed.ncbi.nlm.nih.gov/10569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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