Fialuridine is phosphorylated and inhibits DNA synthesis in isolated rat hepatic mitochondria (Q73233707)

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2 November 2019

title

Fialuridine is phosphorylated and inhibits DNA synthesis in isolated rat hepatic mitochondria (English)

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2 November 2019

author name string

D M Horn

1

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2 November 2019

L A Neeb

2

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2 November 2019

J M Colacino

3

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2 November 2019

F C Richardson

4

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publication date

1 March 1997

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2 November 2019

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2 November 2019

volume

34

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2 November 2019

issue

1

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2 November 2019

page(s)

71-74

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Inhibition of rat kidney mitochondrial DNA, RNA and protein synthesis by halogenated cysteine S-conjugates.

2 November 2019

cites work

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7 January 2021

Cellular and molecular events leading to mitochondrial toxicity of 1-(2-deoxy-2-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil in human liver cells

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7 January 2021

Incorporation of fialuridine (FIAU) into mitochondrial DNA and effects of FIAU on the morphology of mitochondria in human hepatoblastoma cells

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7 January 2021

Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs

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7 January 2021

The mechanism of acute cytotoxicity of triethylphosphine gold(I) complexes. III. Chlorotriethylphosphine gold(I)-induced alterations in isolated rat liver mitochondrial function

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7 January 2021

Mammalian DNA polymerases alpha, beta, gamma, delta, and epsilon incorporate fialuridine (FIAU) monophosphate into DNA and are inhibited competitively by FIAU Triphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2896%2901027-3

7 January 2021

Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis

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7 January 2021

Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.

1 reference

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7 January 2021

Studies on the inhibition of mitochondrial DNA replication by 3'-azido-3'-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication

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7 January 2021

Phosphorylation of the anti-hepatitis B nucleoside analog 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) by human cytosolic and mitochondrial thymidine kinase and implications for cytotoxicity

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7 January 2021

Detection of thymidine kinase activity using an assay based on the precipitation of nucleoside monophosphates with lanthanum chloride

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7 January 2021

10.1016/S0166-3542(96)01027-3

Identifiers

DOI

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2 November 2019

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