The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene (Q73280057)

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2 November 2019

title

The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene (English)

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2 November 2019

author name string

S Oh

1

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2 November 2019

Y Song

2

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2 November 2019

J Yim

3

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2 November 2019

T K Kim

4

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2 November 2019

language of work or name

English

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publication date

1 December 1999

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Journal of Biological Chemistry

2 November 2019

published in

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2 November 2019

volume

274

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2 November 2019

issue

52

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2 November 2019

page(s)

37473-37478

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Telomerase activity, cell proliferation, and cancer

2 November 2019

cites work

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The telomerase reverse transcriptase: components and regulation

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Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?

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hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

21 January 2018

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Telomerase catalytic subunit homologs from fission yeast and human

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Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

21 January 2018

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Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

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Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

21 January 2018

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Direct activation of TERT transcription by c-MYC.

21 January 2018

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Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation

21 January 2018

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Toward identifying a cellular determinant of telomerase repression

21 January 2018

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In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells.

21 January 2018

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Effects of activation-defective TBP mutations on transcription initiation in yeast.

21 January 2018

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Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

21 January 2018

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The mechanism of transcriptional synergy of an in vitro assembled interferon-beta enhanceosome

21 January 2018

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WT1--more than a transcription factor?

21 January 2018

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Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys-Drash syndrome--proof that a tumour-suppressor gene plays a crucial role in normal genitourinary development

21 January 2018

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The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

21 January 2018

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Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition

21 January 2018

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Creation of human tumour cells with defined genetic elements

21 January 2018

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Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms' tumour

21 January 2018

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

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A survey of telomerase activity in human cancer

21 January 2018

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Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.

21 January 2018

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A gene involved in control of human cellular senescence on human chromosome 1q

21 January 2018

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Genetic complementation of the immortal phenotype in group D cell lines by introduction of chromosome 7.

21 January 2018

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Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.

21 January 2018

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Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence

21 January 2018

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Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells

21 January 2018

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Multiple pathways for the regulation of telomerase activity

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.52.37473

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10601322%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference