ICRF-193, a catalytic inhibitor of DNA topoisomerase II, delays the cell cycle progression from metaphase, but not from anaphase to the G1 phase in mammalian cells (Q73309643)

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scientific article published on 01 April 1997

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English	ICRF-193, a catalytic inhibitor of DNA topoisomerase II, delays the cell cycle progression from metaphase, but not from anaphase to the G1 phase in mammalian cells	scientific article published on 01 April 1997

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scholarly article

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2 November 2019

ICRF-193, a catalytic inhibitor of DNA topoisomerase II, delays the cell cycle progression from metaphase, but not from anaphase to the G1 phase in mammalian cells (English)

1 reference

Europe PubMed Central

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2 November 2019

author name string

M Iwai

1

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2 November 2019

A Hara

2

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2 November 2019

T Andoh

3

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2 November 2019

R Ishida

4

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2 November 2019

publication date

1 April 1997

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2 November 2019

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2 November 2019

406

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2 November 2019

3

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2 November 2019

267-270

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2 November 2019

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage

1 reference

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Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle

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Mitotic forces control a cell-cycle checkpoint

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DNA topoisomerases

1 reference

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DNA topoisomerase II is required at the time of mitosis in yeast

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DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

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Chromosome assembly in vitro: Topoisomerase II is required for condensation

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Sister chromatid separation in frog egg extracts requires DNA topoisomerase II activity during anaphase

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Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

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7 January 2021

Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events

1 reference

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7 January 2021

Cyclin is degraded by the ubiquitin pathway

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A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells/.

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Mechanism by which caffeine potentiates lethality of nitrogen mustard

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Chemically induced premature mitosis: differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation

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Structural and mechanical control of mitotic progression

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Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

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Feedback control of the metaphase-anaphase transition in sea urchin zygotes: role of maloriented chromosomes

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Coming undone: how to untangle a chromosome

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Kinetochores, microtubules and the metaphase checkpoint

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Identifiers

10.1016/S0014-5793(97)00282-2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9136899%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

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2 November 2019

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