Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A (Q73318692)

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scientific article published on 01 November 2000

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English	Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A	scientific article published on 01 November 2000

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scholarly article

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3 November 2019

Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A (English)

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3 November 2019

quantitative trait locus

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Jerome I Rotter

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J I Rotter

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3 November 2019

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R M Cantor

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Aldons Jake Lusis

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A J Lusis

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3 November 2019

author name string

C J van der Kallen

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M M van Greevenbroek

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J M Geurts

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F G Bouwman

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B E Aouizerat

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H Allayee

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W A Buurman

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3 November 2019

T W de Bruin

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publication date

1 November 2000

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1381-1391

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11

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3 November 2019

Obesity, atherosclerosis, and coronary artery disease

1 reference

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7 January 2021

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Heredity and body fat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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Genetic models of human obesity--family studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

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The Body-Mass Index of Twins Who Have Been Reared Apart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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Tumor necrosis factor alpha: a key component of the obesity-diabetes link

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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Effects of the obese gene product on body weight regulation in ob/ob mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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Leptin impairs metabolic actions of insulin in isolated rat adipocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Absence of linkage of obesity and energy metabolism to markers flanking homologues of rodent obesity genes in Pima Indians

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationship of a novel polymorphic marker near the human obese (OB) gene to fat mass in healthy women

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel microsatellite polymorphism in the human OB gene: a highly polymorphic marker for linkage analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Autosomal genomic scan for loci linked to obesity and energy metabolism in Pima Indians

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure and sequence variation at the human leptin receptor gene in lean and obese Pima Indians

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Congenital leptin deficiency is associated with severe early-onset obesity in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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Two TNF receptors

1 reference

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7 January 2021

based on heuristic

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The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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The TNF-alpha gene Nco I polymorphism influences the relationship among insulin resistance, percent body fat, and increased serum leptin levels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression pattern of tumour necrosis factor receptors in subcutaneous and omental human adipose tissue: role of obesity and non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma concentrations of soluble TNF-alpha receptors in obese subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationship between plasma leptin levels and the tumor necrosis factor-alpha system in obese subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Complex genetic contribution of the Apo AI-CIII-AIV gene cluster to familial combined hyperlipidemia. Identification of different susceptibility haplotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased plasma concentrations of soluble tumor necrosis factor receptors in sepsis syndrome: correlation with plasma creatinine values.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

The investigation of linkage between a quantitative trait and a marker locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

A more powerful robust sib-pair test of linkage for quantitative traits.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Linkages and associations between the leptin receptor (LEPR) gene and human body composition in the Québec Family Study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic structure of the human OB receptor and identification of two novel intronic microsatellites.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of microsatellite markers linked to the human leptin receptor gene on chromosome 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Genome scan for human obesity and linkage to markers in 20q13.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Suggestive linkages between markers on human 1p32-p22 and body fat and insulin levels in the Quebec Family Study

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic studies of the leptin receptor gene in morbidly obese French Caucasian families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Recessive inheritance of obesity in familial non-insulin-dependent diabetes mellitus, and lack of linkage to nine candidate genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Leptin receptor gene variation and obesity: lack of association in a white British male population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Autocrine inhibition of leptin production by tumor necrosis factor-alpha (TNF-alpha) through TNF-alpha type-I receptor in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of CaM kinase II activation and force maintenance by KN-93 in arterial smooth muscle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

The human obesity gene map: the 1997 update

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Beta 3-adrenergic-receptor polymorphism: a genetic marker for visceral fat obesity and the insulin resistance syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytokines stimulate lipolysis and decrease lipoprotein lipase activity in cultured fat cells by a prostaglandin independent mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0801412

7 January 2021

based on heuristic

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Identifiers

10.1038/SJ.IJO.0801412

1 reference

Europe PubMed Central

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3 November 2019

1 reference

Europe PubMed Central

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3 November 2019

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