An Asp79Asn mutation of the alpha2A-adrenoceptor interferes equally with agonist activation of individual Gialpha-family G protein subtypes (Q73327962)

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3 November 2019

title

An Asp79Asn mutation of the alpha2A-adrenoceptor interferes equally with agonist activation of individual Gialpha-family G protein subtypes (English)

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3 November 2019

author name string

R J Ward

series ordinal

1

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3 November 2019

G Milligan

series ordinal

2

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3 November 2019

publication date

1 December 1999

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3 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10622745%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

462

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3 November 2019

issue

3

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3 November 2019

page(s)

459-463

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A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents

3 November 2019

cites work

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Regulation of p42 and p44 MAP kinase isoforms in Rat-1 fibroblasts stably transfected with alpha 2C10 adrenoreceptors

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Functional interactions of recombinant alpha 2 adrenergic receptor subtypes and G proteins in reconstituted phospholipid vesicles

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Interactions of the alpha2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants

21 January 2018

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Analysis of the relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these polypeptides in rat 1 fibroblasts

21 January 2018

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Molecular Architecture of G Protein-Coupled Receptors.

21 January 2018

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Measurement of agonist-induced guanine nucleotide turnover by the G-protein Gi1alpha when constrained within an alpha2A-adrenoceptor-Gi1alpha fusion protein

21 January 2018

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Hydrophobicity of residue351 of the G protein Gi1 alpha determines the extent of activation by the alpha 2A-adrenoceptor.

21 January 2018

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Delta-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2

21 January 2018

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Rescue of functional interactions between the alpha2A-adrenoreceptor and acylation-resistant forms of Gi1alpha by expressing the proteins from chimeric open reading frames.

21 January 2018

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Agonist occupation of an alpha2A-adrenoreceptor-Gi1alpha fusion protein results in activation of both receptor-linked and endogenous Gi proteins. Comparisons of their contributions to GTPase activity and signal transduction and analysis of receptor-

21 January 2018

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Quantitative analysis of a cysteine351glycine mutation in the G protein Gi1alpha: effect on alpha2A-adrenoceptor-Gi1alpha fusion protein activation

21 January 2018

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In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors

21 January 2018

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Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies

21 January 2018

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Antibodies to the GTP binding protein, Go, antagonize noradrenaline-induced calcium current inhibition in NG108-15 hybrid cells.

21 January 2018

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Kinetics of ternary complex formation with fusion proteins composed of the A(1)-adenosine receptor and G protein alpha-subunits.

21 January 2018

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Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The Beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor

21 January 2018

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GPCR-Galpha fusion proteins: molecular analysis of receptor-G-protein coupling

21 January 2018

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Central hypotensive effects of the alpha2a-adrenergic receptor subtype

21 January 2018

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10.1016/S0014-5793(99)01581-1

21 January 2018

Identifiers

DOI

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3 November 2019

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