Molecular basis for deficient acetaminophen glucuronidation in cats. An interspecies comparison of enzyme kinetics in liver microsomes (Q73394955)

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3 November 2019

title

Molecular basis for deficient acetaminophen glucuronidation in cats. An interspecies comparison of enzyme kinetics in liver microsomes (English)

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3 November 2019

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2

D J Greenblatt

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3 November 2019

1

M H Court

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3 November 2019

language of work or name

English

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publication date

1 April 1997

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3 November 2019

published in

Biochemical Pharmacology

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3 November 2019

volume

53

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3 November 2019

issue

7

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3 November 2019

page(s)

1041-1047

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The conjugation of 1- and 2-naphthols and other phenols in the cat and pig

3 November 2019

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The toxicity and biotransformation of single doses of acetaminophen in dogs and cats

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Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention

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Influence of phenobarbital treatment on p-nitrophenol and bilirubin glucuronidation in Wistar rat, Gunn rat and cat.

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Xenobiotic biotransformation in livestock: comparison to other species commonly used in toxicity testing.

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Hepatic phase I and phase II biotransformations in quail and trout: comparison to other species commonly used in toxicity testing

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Inhibition of acetaminophen and lorazepam glucuronidation in vitro by probenecid

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A method for deriving kinetic constants for two enzymes acting on the same substrate

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Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations.

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The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence

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Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation

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The expression of UDP-glucuronosyltransferases of the UGT1 family in human liver and kidney and in response to drugs

7 January 2021

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Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferases

7 January 2021

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Paracetamol Overdosage Pharmacological Considerations and Clinical Management

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Characterization of paracetamol UDP-glucuronosyltransferase activity in human liver microsomes

7 January 2021

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Optimal detergent activation of rat liver microsomal UDP-glucuronosyl transferases toward morphine and 1-naphthol: contribution to induction and latency studies

7 January 2021

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Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation

7 January 2021

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Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms

7 January 2021

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Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes

7 January 2021

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Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site.

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7 January 2021

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10.1016/S0006-2952(97)00072-5

7 January 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9174118%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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