Structural and functional complementation of an inactive Bcl-2 mutant by Bax truncation (Q73456309)

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4 November 2019

title

Structural and functional complementation of an inactive Bcl-2 mutant by Bax truncation (English)

1 reference

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4 November 2019

author name string

S Ottilie

1

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4 November 2019

J L Diaz

2

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4 November 2019

J Chang

3

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4 November 2019

G Wilson

4

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4 November 2019

K M Tuffo

5

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4 November 2019

S Weeks

6

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4 November 2019

M McConnell

7

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4 November 2019

Y Wang

8

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4 November 2019

T Oltersdorf

9

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4 November 2019

L C Fritz

10

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4 November 2019

language of work or name

English

0 references

publication date

1 July 1997

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Journal of Biological Chemistry

4 November 2019

published in

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4 November 2019

volume

272

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4 November 2019

issue

27

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4 November 2019

page(s)

16955-16961

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The Bcl-2 family of proteins: regulators of cell death and survival

4 November 2019

cites work

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Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.

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Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

21 January 2018

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C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

21 January 2018

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

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Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

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Induction of apoptosis by the Bcl-2 homologue Bak

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Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

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BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

21 January 2018

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Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.

21 January 2018

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Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

21 January 2018

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Combinatorial interaction of human bcl-2 related proteins: mapping of regions important for bcl-2/bcl-x-s interaction.

21 January 2018

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Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax.

21 January 2018

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Bcl-x(S) anatagonizes the protective effects of Bcl-x(L).

21 January 2018

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A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members

21 January 2018

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Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2

21 January 2018

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Bax-independent inhibition of apoptosis by Bcl-XL.

21 January 2018

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

21 January 2018

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Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 January 2018

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Multiple Ras functions can contribute to mammalian cell transformation

21 January 2018

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Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

21 January 2018

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Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K

21 January 2018

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BID: a novel BH3 domain-only death agonist

21 January 2018

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Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

21 January 2018

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Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

21 January 2018

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Interaction and regulation of subcellular localization of CED-4 by CED-9

21 January 2018

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Bcl-x(L) forms an ion channel in synthetic lipid membranes.

21 January 2018

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

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Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.27.16955

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9202007%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference