Systemic administration of 4-chlorokynurenine prevents quinolinate neurotoxicity in the rat hippocampus (Q73525919)

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4 November 2019

title

Systemic administration of 4-chlorokynurenine prevents quinolinate neurotoxicity in the rat hippocampus (English)

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4 November 2019

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Wu HQ

1

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4 November 2019

Lee SC

series ordinal

2

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4 November 2019

Schwarcz R

series ordinal

3

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4 November 2019

language of work or name

English

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publication date

1 March 2000

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European Journal of Pharmacology

4 November 2019

published in

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4 November 2019

volume

390

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4 November 2019

issue

3

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4 November 2019

page(s)

267-274

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The neuroprotective glycine receptor antagonist GV150526 does not produce neuronal vacuolization or cognitive deficits in rats

4 November 2019

cites work

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Protection Against N-methyl-D-aspartate Receptor-Mediated Neuronal Degeneration In Rat Brain by 7-chlorokynurenate and 3-amino-1-hydroxypyrrolid-2-one, Antagonists at The Allosteric Site for Glycine.

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Competitive as well as uncompetitive N-methyl-D-aspartate receptor antagonists affect cortical neuronal morphology and cerebral glucose metabolism

7 January 2021

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7-Chlorokynurenate Blocks NMDA Receptor-Mediated Neurotoxicity in Murine Cortical Culture

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The N-methyl-D-aspartate (NMDA) receptor glycine site antagonist ACEA 1021 does not produce pathological changes in rat brain

7 January 2021

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Facilitated brain uptake of 4-chlorokynurenine and conversion to 7-chlorokynurenic acid.

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7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex

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The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential

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Metabolism of l‐Tryptophan to Kynurenate and Quinolinate in the Central Nervous System: Effects of 6‐Chlorotryptophan and 4‐Chloro‐3‐Hydroxyanthranilate

7 January 2021

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Metabolism of 6-chlorotryptophan to 4-chloro-3-hydroxyanthranilic acid: a potent inhibitor of 3-hydroxyanthranilic acid oxidase

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Indole-2-carboxylates, novel antagonists of the N-methyl-D-aspartate (NMDA)-associated glycine recognition sites: in vivo characterization

7 January 2021

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Enzyme-activated antagonists of the strychnine-insensitive glycine/NMDA receptor

7 January 2021

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Quantitative differences in the effects of de novo produced and exogenous kynurenic acid in rat brain slices

7 January 2021

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Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders

7 January 2021

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Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

7 January 2021

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Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorometric and coulometric electrode array detection

7 January 2021

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On the disposition of intrahippocampally injected kynurenic acid in the rat.

7 January 2021

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Kynurenic Acid in the Quinolinate-lesioned Rat Hippocampus: Studies In Vitro and In Vivo

7 January 2021

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Enzyme-catalyzed production of the neuroprotective NMDA receptor antagonist 7-chlorokynurenic acid in the rat brain in vivo

7 January 2021

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Schizophrenia and glutamatergic transmission

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-2999(00)00024-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10708733%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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