Proteolysis of human bone collagen by cathepsin K: characterization of the cleavage sites generating by cross-linked N-telopeptide neoepitope (Q73531429)

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scientific article published on 01 March 2000

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English	Proteolysis of human bone collagen by cathepsin K: characterization of the cleavage sites generating by cross-linked N-telopeptide neoepitope	scientific article published on 01 March 2000

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scholarly article

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4 November 2019

Proteolysis of human bone collagen by cathepsin K: characterization of the cleavage sites generating by cross-linked N-telopeptide neoepitope (English)

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4 November 2019

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L M Atley

1

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4 November 2019

J S Mort

2

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4 November 2019

M Lalumiere

3

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4 November 2019

D R Eyre

4

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4 November 2019

publication date

1 March 2000

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4 November 2019

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4 November 2019

26

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4 November 2019

3

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4 November 2019

241-247

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4 November 2019

Substrate specificity of recombinant osteoclast-specific cathepsin K from rabbits.

1 reference

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Osteoclasts generate cross-linked collagen N-telopeptides (NTx) but not free pyridinolines when cultured on human bone

1 reference

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7 January 2021

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Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts. Functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme

1 reference

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Hormone replacement therapy in postmenopausal women: urinary N-telopeptide of type I collagen monitors therapeutic effect and predicts response of bone mineral density

1 reference

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Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.

1 reference

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Bone-resorbing agents affect the production and distribution of procollagenase as well as the activity of collagenase in bone tissue

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In vivo and in vitro evidence for the involvement of cysteine proteinases in bone resorption

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Collagenolytic cysteine proteinases of bone tissue. Cathepsin B, (pro)cathepsin L and a cathepsin L-like 70 kDa proteinase

1 reference

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7 January 2021

based on heuristic

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Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cysteine proteinases and matrix metalloproteinases play distinct roles in the subosteoclastic resorption zone.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Degradation of collagen in the bone-resorbing compartment underlying the osteoclast involves both cysteine-proteinases and matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2899%2900270-7

7 January 2021

based on heuristic

inferred from DOI database lookup

The collagenolytic activity of cathepsin K is unique among mammalian proteinases

1 reference

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7 January 2021

based on heuristic

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Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

1 reference

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7 January 2021

based on heuristic

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Application of a new serum assay for type I collagen cross-linked N-telopeptides: assessment of diurnal changes in bone turnover with and without alendronate treatment

1 reference

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7 January 2021

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Monitoring bone resorption in early postmenopausal women by an immunoassay for cross-linked collagen peptides in urine.

1 reference

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7 January 2021

based on heuristic

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A specific immunoassay for monitoring human bone resorption: quantitation of type I collagen cross-linked N-telopeptides in urine

1 reference

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7 January 2021

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Molecular site specificity of pyridinoline and pyrrole cross-links in type I collagen of human bone

1 reference

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7 January 2021

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Role of the occluding loop in cathepsin B activity

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2899%2900270-7

7 January 2021

based on heuristic

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Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorption

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2899%2900270-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2899%2900270-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Fluorescence microscopic demonstration of cathepsin K activity as the major lysosomal cysteine proteinase in osteoclasts.

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2899%2900270-7

7 January 2021

based on heuristic

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Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2899%2900270-7

7 January 2021

based on heuristic

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Interdependency of sequence and positional specificities for cysteine proteases of the papain family

1 reference

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7 January 2021

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Differential regulation of MMP-13 (collagenase-3) and MMP-3 (stromelysin-1) in mouse calvariae

1 reference

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7 January 2021

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Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2899%2900270-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Specificity of urinary excretion of cross-linked N-telopeptides of type I collagen as a marker of bone turnover.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Utility of biochemical markers of bone turnover in the follow-up of patients treated with bisphosphonates

1 reference

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7 January 2021

based on heuristic

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Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

1 reference

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7 January 2021

based on heuristic

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Serum levels of cross-linked N-telopeptides and aminoterminal propeptides of type I collagen indicate low bone mineral density in elderly women

1 reference

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based on heuristic

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On the size of the active site in proteases. I. Papain

1 reference

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7 January 2021

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Urinary excretion of type I collagen crosslinked N-telopeptides in healthy Japanese adults: age- and sex-related changes and reference limits.

1 reference

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based on heuristic

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The effect of hormone replacement therapy in postmenopausal women on urinary C-telopeptide and N-telopeptide of type I collagen, new markers of bone resorption

1 reference

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based on heuristic

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Revised definition of substrate binding sites of papain-like cysteine proteases

1 reference

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7 January 2021

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Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo

1 reference

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Identifiers

10.1016/S8756-3282(99)00270-7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10709996%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10709996%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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