N-terminal determinants of I kappa B alpha necessary for the cytoplasmic regulation of c-Rel (Q73540326)

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4 November 2019

title

N-terminal determinants of I kappa B alpha necessary for the cytoplasmic regulation of c-Rel (English)

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4 November 2019

1

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4 November 2019

author name string

W X Zong

series ordinal

2

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4 November 2019

C Chen

series ordinal

3

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4 November 2019

C Gélinas

series ordinal

4

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4 November 2019

language of work or name

English

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publication date

1 February 2000

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4 November 2019

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4 November 2019

volume

19

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4 November 2019

issue

9

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4 November 2019

page(s)

1239-1244

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203400

4 November 2019

exact match

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cites work

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IkappaB-NF-kappaB structures: at the interface of inflammation control

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Constitutive phosphorylation of I kappa B alpha by casein kinase II.

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I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

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Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

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7 January 2021

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

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Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

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7 January 2021

Autoregulation of I kappa B alpha activity

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7 January 2021

The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers

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7 January 2021

I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

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Common structural constituents confer I kappa B activity to NF-kappa B p105 and I kappa B/MAD-3.

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7 January 2021

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

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7 January 2021

Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity

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7 January 2021

Structure of an IkappaBalpha/NF-kappaB complex

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7 January 2021

Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65.

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7 January 2021

An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha

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7 January 2021

The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation

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7 January 2021

IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

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7 January 2021

I kappa B alpha-mediated inhibition of v-Rel DNA binding requires direct interaction with the RXXRXRXXC Rel/kappa B DNA-binding motif

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7 January 2021

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

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7 January 2021

The N-terminal domain of IkappaB alpha masks the nuclear localization signal(s) of p50 and c-Rel homodimers

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7 January 2021

Distinct domains of IkappaBalpha regulate c-Rel in the cytoplasm and in the nucleus.

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7 January 2021

Ikappa Balpha functions through direct contacts with the nuclear localization signals and the DNA binding sequences of NF-kappaB

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7 January 2021

Catalysis by a multiprotein IkappaB kinase complex

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7 January 2021

A lymphoid cell-specific nuclear factor containing c-Rel-like proteins preferentially interacts with interleukin-6 kappa B-related motifs whose activities are repressed in lymphoid cells

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7 January 2021

Aberrant rel/nfkb genes and activity in human cancer

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Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences

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7 January 2021

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

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7 January 2021

Mechanisms by which IkappaB proteins control NF-kappaB activity

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Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

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7 January 2021

Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

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7 January 2021

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

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7 January 2021

IkappaB kinase: beginning, not the end

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7 January 2021

A mutant Rel-homology domain promotes transcription by p50/NFkappaB1

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7 January 2021

Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA.

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7 January 2021

Nuclear uptake control of NF-kappa B by MAD-3, an I kappa B protein present in the nucleus

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7 January 2021