Alpha-phenyl-tert-butylnitrone (PBN) inhibits NFkappaB activation offering protection against chemically induced diabetes (Q73553429)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10719242%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Alpha-phenyl-tert-butylnitrone (PBN) inhibits NFkappaB activation offering protection against chemically induced diabetes (English)

1 reference

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4 November 2019

author name string

E Ho

series ordinal

1

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4 November 2019

G Chen

series ordinal

2

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4 November 2019

T M Bray

series ordinal

3

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4 November 2019

publication date

1 February 2000

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Free Radical Biology and Medicine

4 November 2019

published in

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4 November 2019

volume

28

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4 November 2019

page(s)

604-614

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4 November 2019

issue

4

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Inheritance of diabetes mellitus

4 November 2019

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Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

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Spin trapping agent, phenyl N-tert-butyl nitrone, inhibits induction of nitric oxide synthase in endotoxin-induced shock in mice

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Protection against oxidative damage to CNS by α-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: A novel series of nonlipid free radical scavengers

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Low dose streptozotocin induced diabetes in mice. Metabolic, light microscopical, histochemical, immunofluorescence microscopical, electron microscopical and morphometrical findings

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[25] Nitric-oxide synthase assays

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Supplementation of N-acetylcysteine inhibits NFkappaB activation and protects against alloxan-induced diabetes in CD-1 mice.

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Evidence for involvement of the proteasome complex (26S) and NFkappaB in IL-1beta-induced nitric oxide and prostaglandin production by rat islets and RINm5F cells

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7 January 2021

Excretion, metabolism and tissue distribution of a spin trapping agent, alpha-phenyl-N-tert-butyl-nitrone (PBN) in rats

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7 January 2021

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7 January 2021

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7 January 2021

Spin trapping agent phenyl N-tert-butylnitrone protects against the onset of drug-induced insulin-dependent diabetes mellitus

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7 January 2021

Inhibition of NF-kappaB, iNOS mRNA, COX2 mRNA, and COX catalytic activity by phenyl-N-tert-butylnitrone (PBN).

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7 January 2021

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Identifiers

DOI

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4 November 2019

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