V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation (Q73574910)

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5 November 2019

title

V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation (English)

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5 November 2019

author name string

M A Bogue

1

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5 November 2019

C Wang

2

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5 November 2019

C Zhu

3

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5 November 2019

D B Roth

4

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5 November 2019

publication date

1 July 1997

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5 November 2019

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5 November 2019

volume

7

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5 November 2019

issue

1

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5 November 2019

page(s)

37-47

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Normal D-JH rearranged products of the IgH gene in SCID mouse bone marrow.

5 November 2019

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

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7 January 2021

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Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny

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Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

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7 January 2021

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

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7 January 2021

Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity

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Biased T-cell receptor delta element recombination in scid thymocytes

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Enumeration and characterization of DJH structures in mouse fetal liver

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Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

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Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

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Initiation of V(D)J recombination in vitro obeying the 12/23 rule

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Influence of the V(D)J recombination mechanism on the formation of the primary T and B cell repertoires

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7 January 2021

DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

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7 January 2021

Abnormal deletions in the T-cell receptor delta locus of mouse thymocytes

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7 January 2021

Extent to which homology can constrain coding exon junctional diversity in V(D)J recombination

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7 January 2021

Sequence-specific DNA binding by Ku autoantigen and its effects on transcription

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7 January 2021

Mice lacking TdT: mature animals with an immature lymphocyte repertoire

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7 January 2021

Mice lacking terminal deoxynucleotidyl transferase: adult mice with a fetal antigen receptor repertoire

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7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

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7 January 2021

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation

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7 January 2021

Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products

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7 January 2021

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

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7 January 2021

DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

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7 January 2021

T cell receptor gamma and delta gene junctional sequences in SCID mice: excessive P nucleotide insertion

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7 January 2021

Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

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7 January 2021

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

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7 January 2021

P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells

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7 January 2021

Novel strand exchanges in V(D)J recombination

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7 January 2021

Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen

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7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

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7 January 2021

Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA.

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7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

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7 January 2021

Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints

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7 January 2021

The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability

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7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

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7 January 2021

P nucleotides in V(D)J recombination: a fine-structure analysis

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7 January 2021

The V(D)J recombination defect in the xrs-6 cell line results from a point mutation in the Ku80 gene

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7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

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7 January 2021

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7 January 2021

High frequency of normal DJH joints in B cell progenitors in severe combined immunodeficiency mice

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7 January 2021

V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair

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7 January 2021

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7 January 2021

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7 January 2021

Comparison of filler DNA at immune, nonimmune, and oncogenic rearrangements suggests multiple mechanisms of formation

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7 January 2021

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

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7 January 2021

Characterization of broken DNA molecules associated with V(D)J recombination

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7 January 2021

Repair and Recombination: How to make ends meet

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7 January 2021

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

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7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

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7 January 2021

Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription

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7 January 2021

Coding joint formation of endogenous T cell receptor genes in lymphoid cells from scid mice: unusual P-nucleotide additions in VJ-coding joints

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7 January 2021

Inversions produced during V(D)J rearrangement at IgH, the immunoglobulin heavy-chain locus

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7 January 2021

The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo

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7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

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7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

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7 January 2021

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7 January 2021

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

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7 January 2021

Initiation of V(D)J recombination in a cell-free system.

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7 January 2021

The role of short homology repeats and TdT in generation of the invariant gamma delta antigen receptor repertoire in the fetal thymus.

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7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

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7 January 2021

Characterization of coding ends in thymocytes of scid mice: Implications for the mechanism of V(D)J recombination

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7 January 2021

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Identifiers

DOI

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5 November 2019

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