Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes (Q73666696)

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5 November 2019

title

Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes (English)

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5 November 2019

author name string

Y Wang

series ordinal

1

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5 November 2019

J D Unadkat

series ordinal

2

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5 November 2019

publication date

1 October 1999

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Biopharmaceutics and Drug Disposition

5 November 2019

published in

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5 November 2019

volume

20

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5 November 2019

issue

7

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5 November 2019

page(s)

341-346

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In-vitro characterization of the cytochrome P450 isoenzymes involved in the back oxidation and N-dealkylation of reduced haloperidol.

5 November 2019

cites work

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Metabolism of Zaleplon by human hepatic microsomal cytochrome P450 isoforms

21 January 2018

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Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol

21 January 2018

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Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily

21 January 2018

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Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.

21 January 2018

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Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

21 January 2018

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Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

21 January 2018

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Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations

21 January 2018

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Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

21 January 2018

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Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

21 January 2018

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Inhibitory monoclonal antibody to human cytochrome P450 2B6.

21 January 2018

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Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450.

21 January 2018

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Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes

21 January 2018

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Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.

21 January 2018

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Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline

21 January 2018

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Differential inhibition of coumarin 7-hydroxylase activity in mouse and human liver microsomes

21 January 2018

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Potent inhibition of yeast-expressed CYP2D6 by dihydroquinidine, quinidine, and its metabolites

21 January 2018

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Examination of purported probes of human CYP2B6.

21 January 2018

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10.1002/(SICI)1099-081X(199910)20:7<341::AID-BDD195>3.0.CO;2-F

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10760842%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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