Distinct type-2A protein phosphatases activate HMGCoA reductase and acetyl-CoA carboxylase in liver (Q73674284)

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5 November 2019

title

Distinct type-2A protein phosphatases activate HMGCoA reductase and acetyl-CoA carboxylase in liver (English)

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5 November 2019

4

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5 November 2019

author name string

V Gaussin

1

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5 November 2019

P Skarlas

2

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5 November 2019

Y P Ching

3

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5 November 2019

L Hue

5

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5 November 2019

publication date

1 August 1997

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5 November 2019

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5 November 2019

volume

413

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5 November 2019

issue

1

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5 November 2019

page(s)

115-118

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The low activity of acetyl-CoA carboxylase in basal and glucagon-stimulated hepatocytes is due to phosphorylation by the AMP-activated protein kinase and not cyclic AMP-dependent protein kinase.

5 November 2019

cites work

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Evidence that insulin activates fat-cell acetyl-CoA carboxylase by increased phosphorylation at a specific site

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Swelling of rat hepatocytes activates acetyl-CoA carboxylase in parallel to glycogen synthase

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Mechanism of activation of liver acetyl-CoA carboxylase by cell swelling

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Stimulation of glycogen synthesis in hepatocytes by added amino acids is related to the total intracellular content of amino acids

21 January 2018

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Activation of hepatic acetyl-CoA carboxylase by glutamate and Mg2+ is mediated by protein phosphatase-2A.

21 January 2018

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3-Hydroxy-3-methylglutaryl-CoA reductase: a transmembrane glycoprotein of the endoplasmic reticulum with N-linked "high-mannose" oligosaccharides

21 January 2018

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Conditions that result in the mobilization and influx of Ca2+ into rat hepatocytes induce the rapid loss of 3-hydroxy-3-methylglutaryl-CoA reductase activity that is not reversed by phosphatase treatment

21 January 2018

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Diurnal rhythm of phosphorylation of rat liver acetyl-CoA carboxylase by the AMP-activated protein kinase, demonstrated using freeze-clamping. Effects of high fat diets

21 January 2018

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Diurnal changes in the fraction of 3-hydroxy-3-methylglutaryl-CoA reductase in the active form in rat liver microsomal fractions

21 January 2018

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Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay

21 January 2018

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Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities

21 January 2018

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Analysis of the specificity of the AMP-activated protein kinase by site-directed mutagenesis of bacterially expressed 3-hydroxy 3-methylglutaryl-CoA reductase, using a single primer variant of the unique-site-elimination method

21 January 2018

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Control of gluconeogenesis and of enzymes of glycogen metabolism in isolated rat hepatocytes. A parallel study of the effect of phenylephrine and of glucagon

21 January 2018

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Untersuchungen uber die Harnstoffbildung im Tierkörper

21 January 2018

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Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP-activated protein kinase. A sensitive mechanism to protect the cell against ATP depletion

21 January 2018

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In situ measurement of HMG-CoA reductase activity in digitonin-permeabilized hepatocytes

21 January 2018

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Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase

21 January 2018

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5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?

21 January 2018

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The pathway of adenine nucleotide catabolism and its control in isolated rat hepatocytes subjected to anoxia

21 January 2018

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Serine/threonine protein phosphatases

21 January 2018

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The protein phosphatases involved in cellular regulation. 2. Glycogen metabolism

21 January 2018

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Purification and Subunit Structure of a High-Molecular-Weight Phosphoprotein Phosphatase (Phosphatase 11) from Rat Liver

21 January 2018

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The protein phosphatases involved in cellular regulation. 3. Fatty acid synthesis, cholesterol synthesis and glycolysis/gluconeogenesis

21 January 2018

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Modulation of rat liver hydroxymethylglutaryl-CoA reductase by protein phosphatases: purification of nonspecific hydroxymethylglutaryl-CoA reductase phosphatases

21 January 2018

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21 January 2018

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Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase

21 January 2018

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Purification and Subunit Structure of Rat-Liver Phosphoprotein Phosphatase whose Molecular Weight is 260000 by Gel Filtration (Phosphatase IB)

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-5793(97)00890-9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9287127%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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