Effects of apolipoprotein E (apoE) isoforms, beta-amyloid (Abeta) and apoE/Abeta complexes on protein kinase C-alpha (PKC-alpha) translocation and amyloid precursor protein (APP) processing in human SH-SY5Y neuroblastoma cells and fibroblasts (Q73719722)

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scientific article published on 01 June 2001

Language	Label	Description	Also known as
English	Effects of apolipoprotein E (apoE) isoforms, beta-amyloid (Abeta) and apoE/Abeta complexes on protein kinase C-alpha (PKC-alpha) translocation and amyloid precursor protein (APP) processing in human SH-SY5Y neuroblastoma cells and fibroblasts	scientific article published on 01 June 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11290387%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Effects of apolipoprotein E (apoE) isoforms, beta-amyloid (Abeta) and apoE/Abeta complexes on protein kinase C-alpha (PKC-alpha) translocation and amyloid precursor protein (APP) processing in human SH-SY5Y neuroblastoma cells and fibroblasts (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11290387%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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B Wiehager

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11290387%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

M Hüttinger

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11290387%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

R F Cowburn

5

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6 November 2019

publication date

1 June 2001

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6 November 2019

Neurochemistry International

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6 November 2019

38

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6 November 2019

7

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6 November 2019

615-625

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11290387%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene.

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Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

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7 January 2021

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The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein

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Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing

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A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia.

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Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

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Nicergoline stimulates protein kinase C mediated alpha-secretase processing of the amyloid precursor protein in cultured human neuroblastoma SH-SY5Y cells

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Action of amyloid beta-protein on protein kinase C activity.

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Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells

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7 January 2021

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Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive

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Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts

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Inhibition of beta-amyloid production by activation of protein kinase C.

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7 January 2021

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Apolipoprotein E and cholesterol affect neuronal calcium signalling: the possible relationship to beta-amyloid neurotoxicity

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7 January 2021

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Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain

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7 January 2021

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Conventional protein kinase C (PKC)-alpha and novel PKC epsilon, but not -delta, increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 fibroblasts

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The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma

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Saturation and suppression of hepatic lipoprotein receptors: a mechanism for the hypercholesterolemia of cholesterol-fed rabbits

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7 January 2021

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Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

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7 January 2021

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

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A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease.

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7 January 2021

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Apolipoprotein E and the CNS response to injury.

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7 January 2021

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β‐Amyloid1–40 Increases Expression of β‐Amyloid Precursor Protein in Neuronal Hybrid Cells

1 reference

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7 January 2021

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Protein kinase C activation increases release of secreted amyloid precursor protein without decreasing Abeta production in human primary neuron cultures.

1 reference

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7 January 2021

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Physiological levels of beta-amyloid peptide stimulate protein kinase C in PC12 cells

1 reference

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7 January 2021

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Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

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Differential involvement of protein kinase C isozymes in Alzheimer's disease

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Regulation of amyloid precursor protein cleavage

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Apolipoprotein E isoforms increase intracellular Ca2+ differentially through a omega-agatoxin IVa-sensitive Ca2+-channel

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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

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Amyloid beta-protein(25-35) increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells

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Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

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1 reference

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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Identifiers

10.1016/S0197-0186(00)00128-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11290387%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11290387%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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