Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953 (Q73745592)

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scientific article published on 01 August 2003

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English	Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953	scientific article published on 01 August 2003

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6 November 2019

Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953 (English)

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6 November 2019

Saccharomyces cerevisiae

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José María Pérez-Victoria

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6 November 2019

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André Goffeau

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6 November 2019

Gwenaëlle Conseil

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Gwenaëlle Conseil

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6 November 2019

Attilio Di Pietro

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Attilio Di Pietro

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6 November 2019

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J Michel Renoir

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6 November 2019

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1 August 2003

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6 November 2019

Biochimica et Biophysica Acta

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6 November 2019

1614

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6 November 2019

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6 November 2019

131-134

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6 November 2019

Saccharomyces cerevisiae YDR1, which encodes a member of the ATP-binding cassette (ABC) superfamily, is required for multidrug resistance

1 reference

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7 January 2021

Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900193-7

7 January 2021

In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network

1 reference

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7 January 2021

Prenyl-flavonoids as potent inhibitors of the Pdr5p multidrug ABC transporter from Saccharomyces cerevisiae.

1 reference

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7 January 2021

Protein kinase C effectors bind to multidrug ABC transporters and inhibit their activity

1 reference

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7 January 2021

LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones

1 reference

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7 January 2021

The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo

1 reference

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7 January 2021

Characterisation of human steroid hormone transport mediated by Cdr1p, a multidrug transporter of Candida albicans, belonging to the ATP binding cassette super family.

1 reference

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7 January 2021

P-glycoprotein transports corticosterone and is photoaffinity-labeled by the steroid

1 reference

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7 January 2021

Progesterone and its metabolites: the potent inhibitors of the transporting activity of P-glycoprotein in the adrenal gland

1 reference

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7 January 2021

Steroid treatment, accumulation, and antagonism of P-glycoprotein in multidrug-resistant cells.

1 reference

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7 January 2021

The antiprogestatin drug RU 486 potentiates doxorubicin cytotoxicity in multidrug resistant cells through inhibition of P-glycoprotein function.

1 reference

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7 January 2021

RU49953: a non-hormonal steroid derivative that potently inhibits P-glycoprotein and reverts cellular multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2803%2900193-7

7 January 2021

Binding of steroid modulators to recombinant cytosolic domain from mouse P-glycoprotein in close proximity to the ATP site.

1 reference

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7 January 2021

ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p

1 reference

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7 January 2021

Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters

1 reference

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7 January 2021

Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates

1 reference

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7 January 2021

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

1 reference

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7 January 2021

Identifiers

10.1016/S0005-2736(03)00193-7

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12896805%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12896805%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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