Comparison of human cytomegalovirus DNA polymerase activity for ganciclovir-resistant and -sensitive clinical strains (Q73787872)

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6 November 2019

title

Comparison of human cytomegalovirus DNA polymerase activity for ganciclovir-resistant and -sensitive clinical strains (English)

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6 November 2019

author name string

M Kariya

series ordinal

1

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6 November 2019

S Mori

series ordinal

2

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6 November 2019

Y Eizuru

series ordinal

3

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6 November 2019

publication date

1 February 2000

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6 November 2019

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6 November 2019

volume

45

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6 November 2019

issue

2

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6 November 2019

page(s)

115-122

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A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate

6 November 2019

cites work

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7 January 2021

Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recov

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7 January 2021

A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerases

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7 January 2021

A general structure for DNA-dependent DNA polymerases.

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Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease

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7 January 2021

A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture

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7 January 2021

Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients

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7 January 2021

Genetic analysis of a clinical isolate of human cytomegalovirus exhibiting resistance against both ganciclovir and cidofovir

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7 January 2021

Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS.

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7 January 2021

Herpes simplex virus type 1 DNA polymerase. Mutational analysis of the 3'-5'-exonuclease domain

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7 January 2021

Intravenous cidofovir for peripheral cytomegalovirus retinitis in patients with AIDS. A randomized, controlled trial

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7 January 2021

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

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7 January 2021

Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir.

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7 January 2021

Human cytomegalovirus-induced DNA polymerase and its interaction with the triphosphates of 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-methyluracil, -5-iodocytosine, and -5-methylcytosine

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7 January 2021

Characterization of human cytomegalovirus-induced DNA polymerase and the associated 3'-to-5', exonuclease

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7 January 2021

Murine cytomegalovirus DNA polymerase: Purification, characterization and role in the antiviral activity of acyclovir

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7 January 2021

Progressive retinitis-encephalitis due to ganciclovir-resistant cytomegalovirus associated with aplastic anemia

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7 January 2021

High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes

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7 January 2021

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

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7 January 2021

Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma

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7 January 2021

10.1016/S0166-3542(00)00063-2

Identifiers

DOI

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6 November 2019

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