Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway (Q73806599)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

Armelle Calipel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Gaelle Lefevre

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Celio Pouponnot

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Frédéric Mouriaux

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Frédéric Mascarelli

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

0 references

publication date

12 August 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

6 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

42409-42418

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

issue

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

cites work

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

The Raf/MEK/ERK pathway: new concepts of activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

No N-ras mutations in human uveal melanoma: the role of ultraviolet light revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Murine Ksr interacts with MEK and inhibits Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Blocking oncogenic Ras signaling for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Nitric oxide and N-acetylcysteine inhibit the activation of mitogen-activated protein kinases by angiotensin II in rat cardiac fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

KSR is a scaffold required for activation of the ERK/MAPK module

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Induction of postmitotic neuroretina cell proliferation by distinct Ras downstream signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Control of the eukaryotic cell cycle by MAP kinase signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Nerve Growth Factor-mediated Activation of the Mitogen-activated Protein (MAP) Kinase Cascade Involves a Signaling Complex Containing B-Raf and HSP90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

MAP kinase-dependent degradation of p27Kip1 by calpains in choroidal melanoma cells. Requirement of p27Kip1 nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

B-raf, a new member of the raf family, is activated by DNA rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

BRAF Mutation in Papillary Thyroid Carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

A p34(cdc2) survival checkpoint in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Mitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

The prognostic value of cyclin D1, p53, and MDM2 protein expression in uveal melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Redundant cyclin overexpression and gene amplification in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Expression and prognostic role of cyclin-dependent kinase 1 (cdc2) in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Multiple ras effector pathways contribute to G(1) cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Absence of BRAF gene mutations in uveal melanomas in contrast to cutaneous melanomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Lack of BRAF mutation in primary uveal melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Pathways to melanoma development: lessons from the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Genetic alterations of p16INK4a and p53 genes in sporadic dysplastic nevus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Constitutional alterations in p16 in patients with uveal melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

Individuals with presumably hereditary uveal melanoma do not harbour germline mutations in the coding regions of either the P16INK4A, P14ARF or cdk4 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308709200

21 January 2018

Identifiers

DOI

10.1074/JBC.M308709200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12917419%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference