On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models (Q73835480)

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7 November 2019

review article

1 reference

title

On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11336779%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

1 reference

Z Galdzicki

1

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7 November 2019

R Siarey

2

1 reference

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7 November 2019

R Pearce

3

1 reference

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7 November 2019

J Stoll

4

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7 November 2019

S I Rapoport

5

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7 November 2019

publication date

1 April 2001

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7 November 2019

volume

35

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7 November 2019

issue

2

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7 November 2019

page(s)

115-145

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Induction and reversal of long-term potentiation by repeated high-frequency stimulation in rat hippocampal slices

7 November 2019

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Long-term intracerebral transplants of fetal hippocampus from mouse trisomy 16, a model for Down's syndrome (trisomy 21), do not exhibit Alzheimer's disease neuropathology by ultrastructural criteria .

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Kainate reveals its targets

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Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis.

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Essential role of the nerve growth factor in the survival and maintenance of dissociated sensory and sympathetic embryonic nerve cells in vitro

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The NMDA receptor subunit 2B locus (Nmdar2b) maps to the distal end of murine chromosome 6

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7 January 2021

Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Structural abnormalities of the cerebral cortex in human chromosomal aberrations: a Golgi study.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Pyramidal cell abnormalities in the motor cortex of a child with Down's syndrome. A Golgi study

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

A murine model for Down syndrome shows reduced responsiveness to pain.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Effect of basic fibroblast growth factor on neurons cultured from various regions of postnatal rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Action potential waveform voltage-clamp commands reveal striking differences in calcium entry via low and high voltage activated calcium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Long-term synaptic enhancement and short-term potentiation in rat fascia dentata act through different mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Antiproteases and Down's syndrome in an Australian population

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

The nerve growth factor family of receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Cholinergic, serotonergic and catecholaminergic neurons are not affected in Ts65Dn mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Response to atropine in Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Neuropathology in Patients with Congenital Heart Disease and Down Syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Impaired Ca-signaling in astrocytes from the Ts16 mouse model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Gene structure and chromosomal localization of the mouse NMDA receptor channel subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Cerebral cortical astroglia from the trisomy 16 mouse, a model for down syndrome, produce neuronal cholinergic deficits in cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Electrical properties of cultured dorsal root ganglion neurons from normal and trisomy 21 human fetal tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Functional modulation of brain sodium channels by protein kinase C phosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Electrophysiological properties of cultured dorsal root ganglion and spinal cord neurons of normal and trisomy 16 fetal mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Neurochemical Changes in Murine Trisomy 16: Delay in Cholinergic and Catecholaminergic Systems

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

High-affinity zinc inhibition of NMDA NR1-NR2A receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Decreased sensitivity to nerve growth factor of dorsal root ganglion neurons cultured from mouse trisomy 16, a model of Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Differential expression of membrane currents in dissociated mouse primary sensory neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Oxidative stress mediates impairment of muscle function in transgenic mice with elevated level of wild-type Cu/Zn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Free radicals accelerate the decay of long-term potentiation in field CA1 of guinea-pig hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Abnormal chloride and potassium conductances in cultured embryonic tongue muscle from trisomy 16 mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Molecular biology of calcium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Multiple calcium channels mediate neurotransmitter release from peripheral neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Murine trisomy 16 model of Down's syndrome: central nervous system electron microscopic observations

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Seizure Disorders in Down Syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Differential effects of subunit interactions on protein kinase A- and C-mediated phosphorylation of L-type calcium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Dendritic Spine "Dysgenesis" and Mental Retardation

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

How did the human brain evolve? A proposal based on new evidence from in vivo brain imaging during attention and ideation

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

The effect of nerve growth factor on the development of sodium channels in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

1 reference

7 January 2021

Genetic basis for a mouse model of Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

A mouse model for Down syndrome exhibits learning and behaviour deficits.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Amino acid neurotransmitter deficits in adult Down's syndrome brain tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Nerve growth factor expression in the developing hippocampus isolated in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Nerve growth factor induces increased expression of a laminin-binding integrin in rat pheochromocytoma PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

The sodium current underlying action potentials in guinea pig hippocampal CA1 neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Quantitative CT analysis of brain morphometry in adult Down's syndrome at different ages.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Serial quantitative CT analysis of brain morphometrics in adult Down's syndrome at different ages

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Alteration of cellular adhesion by nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

In cortical cultures of trisomy 16 mouse brain the upregulated metallothionein-I/II fails to respond to H2O2 exposure or glutamate receptor stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Non-disjunction of chromosome 21 in maternal meiosis I: evidence for a maternal age-dependent mechanism involving reduced recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Assay of myo-inositol in cerebrospinal fluid and plasma by chemical ionization mass spectrometry of the hexaacetate derivative

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Polyol profiles in Down syndrome. myo-Inositol, specifically, is elevated in the cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Responses to NMDA in cultured hippocampal neurons from trisomy 16 embryonic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Morphologic and neurochemical studies of embryonic brain development in murine trisomy 16

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Age-dependent control of dorsal root ganglion neuron survival by macromolecular and low-molecular-weight trophic agents and substratum-bound laminins.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Glutathione levels and nerve cell loss in hippocampal cultures from trisomy 16 mouse--a model of Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Seizures in children with Down syndrome: etiology, characteristics and outcome.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Do septal neurons pace the hippocampal theta rhythm?

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Long-term transplants of mouse trisomy 16 hippocampal neurons, a model for Down's syndrome, do not develop Alzheimer's disease neuropathology.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Reduced expression of voltage-gated sodium channels in neurons cultured from trisomy 16 mouse hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Active propagation of somatic action potentials into neocortical pyramidal cell dendrites

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Neurogenesis of the basal forebrain in euploid and trisomy 16 mice: an animal model for developmental disorders in Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Abnormal neuronal development in the visual cortex of the human fetus and infant with down's syndrome. A quantitative and qualitative Golgi study.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Restoration of excitation-contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

A single B1 subunit mapped to mouse chromosome 7 may be a common component of Na channel isoforms from brain, skeletal muscle and heart.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Calcium channels, stores, and oscillations

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

The synaptic activation of kainate receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Molecular genetics of human chromosome 21.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Phosphorylation and inhibition of type III adenylyl cyclase by calmodulin-dependent protein kinase II in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

The involvement of L-type calcium channels in heterosynaptic long-term depression in the hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Modulation and block of ion channels: a new biology of polyamines

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

The Golgi rapid method in clinical neuropathology: the morphologic consequences of suboptimal fixation

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

N-acetylaspartylglutamate activates cyclic AMP-coupled metabotropic glutamate receptors in cerebellar astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Protein kinase C-mediated down-regulation of voltage-dependent sodium channels in adrenal chromaffin cells

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

Mechanism of transmitter release: voltage hypothesis and calcium hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0926-6410%2800%2900074-4

7 January 2021

10.1016/S0926-6410(00)00074-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11336779%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference