Analysis of telomerase processivity: mechanistic similarity to HIV-1 reverse transcriptase and role in telomere maintenance (Q74113048)

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9 November 2019

title

Analysis of telomerase processivity: mechanistic similarity to HIV-1 reverse transcriptase and role in telomere maintenance (English)

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9 November 2019

author name string

Y Peng

series ordinal

1

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9 November 2019

I S Mian

series ordinal

2

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9 November 2019

N F Lue

series ordinal

3

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9 November 2019

publication date

1 June 2001

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9 November 2019

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9 November 2019

volume

7

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9 November 2019

issue

6

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9 November 2019

page(s)

1201-1211

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The processivity of DNA synthesis exhibited by drug-resistant variants of human immunodeficiency virus type-1 reverse transcriptase

9 November 2019

cites work

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Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

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Reconstitution of human telomerase activity in vitro

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Telomerase and the maintenance of chromosome ends

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A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity

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Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax

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Secondary structure of vertebrate telomerase RNA

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The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex

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Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

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7 January 2021

Telomerase and retrotransposons: which came first?

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Est1 and Cdc13 as comediators of telomerase access

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Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

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Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants

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Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

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7 January 2021

Telomerase is processive

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7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

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7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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7 January 2021

Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomycespombe

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7 January 2021

Human telomerase contains evolutionarily conserved catalytic and structural subunits

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7 January 2021

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

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7 January 2021

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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7 January 2021

The Est3 protein is a subunit of yeast telomerase

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7 January 2021

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

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7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

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7 January 2021

Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang

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7 January 2021

Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity

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7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

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7 January 2021

Negative regulation of yeast telomerase activity through an interaction with an upstream region of the DNA primer

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7 January 2021

Species-specific and sequence-specific recognition of the dG-rich strand of telomeres by yeast telomerase

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7 January 2021

Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans

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7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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7 January 2021

Template definition by Tetrahymena telomerase reverse transcriptase

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7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

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7 January 2021

Reversing time: origin of telomerase

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

The telomerase reverse transcriptase: components and regulation

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7 January 2021

Molecular cloning and characterization of AtTERT, a telomerase reverse transcriptase homolog in Arabidopsis thaliana

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7 January 2021

Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro

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7 January 2021

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

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Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase

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Identifiers

DOI

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9 November 2019

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