Strong inhibition of neuronal nitric oxide synthase by the calmodulin antagonist and anti-estrogen drug tamoxifen (Q74178114)

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9 November 2019

title

Strong inhibition of neuronal nitric oxide synthase by the calmodulin antagonist and anti-estrogen drug tamoxifen (English)

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9 November 2019

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A Renodon

1

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9 November 2019

J L Boucher

2

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9 November 2019

M A Sari

3

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9 November 2019

M Delaforge

4

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9 November 2019

J Ouazzani

5

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9 November 2019

D Mansuy

6

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9 November 2019

language of work or name

English

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publication date

1 November 1997

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9 November 2019

published in

Biochemical Pharmacology

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9 November 2019

volume

54

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9 November 2019

issue

10

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9 November 2019

page(s)

1109-1114

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Tamoxifen: toxicities and drug resistance during the treatment and prevention of breast cancer

9 November 2019

cites work

1 reference

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Fourteenth Gaddum Memorial Lecture. A current view of tamoxifen for the treatment and prevention of breast cancer

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Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer

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Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells

7 January 2021

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Chemoprevention of breast cancer by tamoxifen: risks and opportunities

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Tamoxifen is a calmodulin antagonist in the activation of cAMP phosphodiesterase

7 January 2021

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Variation of the inhibition of calmodulin dependent cyclic AMP phosphodiesterase amongst analogues of tamoxifen; correlations with cytotoxicity

7 January 2021

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Synergistic induction of apoptosis in breast cancer cells by tamoxifen and calmodulin inhibitors.

7 January 2021

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A molecular modeling study of the interactions between the antiestrogen drug tamoxifen and several derivatives, and the calcium-binding protein calmodulin

7 January 2021

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Rationally designed analogues of tamoxifen with improved calmodulin antagonism

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The arginine-nitric oxide pathway: a target for new drugs.

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Nitric oxide: a new paradigm for second messengers.

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Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions.

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Neuronal nitric oxide synthase, a modular enzyme formed by convergent evolution: structure studies of a cysteine thiolate-liganded heme protein that hydroxylates L-arginine to produce NO. as a cellular signal.

7 January 2021

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Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer

7 January 2021

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Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes

7 January 2021

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The FUR1 gene of Saccharomyces cerevisiae: cloning, structure and expression of wild-type and mutant alleles

7 January 2021

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Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5.

7 January 2021

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Maximizing the expression of mammalian cytochrome P-450 monooxygenase activities in yeast cells

7 January 2021

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Characterization of rat neuronal nitric oxide synthase expressed in Saccharomyces cerevisiae.

7 January 2021

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Expression in yeast and purification of functional macrophage nitric oxide synthase. Evidence for cysteine-194 as iron proximal ligand.

7 January 2021

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Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

7 January 2021

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

7 January 2021

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Dye Uptake Methods for Assessing Viral Cytopathogenicity and their Application to Interferon Assays

7 January 2021

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Inhibition of neuronal nitric oxide synthase by antipsychotic drugs

7 January 2021

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Nitric oxide synthase activity in human breast cancer

7 January 2021

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Estrogen increases endothelial nitric oxide by a receptor-mediated system

7 January 2021

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10.1016/S0006-2952(97)00316-X

7 January 2021

Identifiers

DOI

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9 November 2019

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