Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors (Q74271971)

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9 November 2019

review article

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title

Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors (English)

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9 November 2019

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Yenari MA

1

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9 November 2019

Dumas TC

series ordinal

2

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9 November 2019

Sapolsky RM

series ordinal

3

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9 November 2019

Steinberg GK

series ordinal

4

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9 November 2019

publication date

1 July 2001

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9 November 2019

published in

Neurological Research

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9 November 2019

volume

23

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9 November 2019

issue

5

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9 November 2019

page(s)

543-552

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Mitochondria and apoptosis

9 November 2019

cites work

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Gene therapy using viral vectors for acute neurologic insults

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

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Molecular analysis of neuronal physiology by gene transfer into neurons with herpes simplex virus vectors

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Gene transfer to neurons using herpes simplex virus-based vectors

21 January 2018

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Defective herpes simplex virus vectors expressing the rat brain stress-inducible heat shock protein 72 protect cultured neurons from severe heat shock.

21 January 2018

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Amplicon-based herpes simplex virus vectors.

21 January 2018

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Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults.

21 January 2018

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Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy

21 January 2018

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Altering central nervous system physiology with a defective herpes simplex virus vector expressing the glucose transporter gene

21 January 2018

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Overexpression of the glucose transporter gene with a herpes simplex viral vector protects striatal neurons against stroke.

21 January 2018

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An adenoviral vector expressing the glucose transporter protects cultured striatal neurons from 3-nitropropionic acid

21 January 2018

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A herpes simplex virus vector overexpressing the glucose transporter gene protects the rat dentate gyrus from an antimetabolite toxin

21 January 2018

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Herpes simplex virus vectors overexpressing the glucose transporter gene protect against seizure-induced neuron loss

21 January 2018

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Calbindin d28k overexpression protects striatal neurons from transient focal cerebral ischemia

21 January 2018

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Calbindin D28K gene transfer via herpes simplex virus amplicon vector decreases hippocampal damage in vivo following neurotoxic insults

21 January 2018

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Calbindin-D28k immunoreactivity and selective vulnerability to ischemia in the dentate gyrus of the developing rat.

21 January 2018

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Evidence for calcium-reducing and excitoprotective roles for the calcium-binding protein calbindin-1328k in cultured hippocampal neurons

21 January 2018

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Brain injury and tumor necrosis factors induce calbindin D-28k in astrocytes: evidence for a cytoprotective response

21 January 2018

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Regulation of excitatory transmission at hippocampal synapses by calbindin D28k

21 January 2018

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Stress proteins and tolerance to focal cerebral ischemia.

21 January 2018

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HSP70 protects murine astrocytes from glucose deprivation injury.

21 January 2018

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Transgenic mice expressing the human inducible Hsp70 have hippocampal neurons resistant to ischemic injury

21 January 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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bcl-2 inhibits death of central neural cells induced by multiple agents

21 January 2018

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BCL-2 prevents killing of neuronal cells by glutamate but not by amyloid beta protein

21 January 2018

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A bcl-2 expressing viral vector protects cortical neurons from excitotoxicity even when administered several hours after the toxic insult.

21 January 2018

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Expression of bcl-2 inhibits necrotic neural cell death.

21 January 2018

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BCL-2 blocks glutamate toxicity in neural cell lines

21 January 2018

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The protooncogene bcl-2 inhibits apoptosis in PC12 cells

21 January 2018

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Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

21 January 2018

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The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis.

21 January 2018

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Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia.

21 January 2018

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Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats.

21 January 2018

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Alterations of Bcl-2 family proteins precede cytoskeletal proteolysis in the penumbra, but not in infarct centres following focal cerebral ischemia in mice.

21 January 2018

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Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke

21 January 2018

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Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia

21 January 2018

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Limitations in the neuroprotective potential of gene therapy with Bcl-2.

21 January 2018

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Heat-shock protein protection.

21 January 2018

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Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.

21 January 2018

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Sparing of neuronal function postseizure with gene therapy

21 January 2018

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Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing?

21 January 2018

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A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction

21 January 2018

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Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11474812%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference