Further evaluation of COMPACT, the molecular orbital approach for the prospective safety evaluation of chemicals (Q74330367)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Further evaluation of COMPACT, the molecular orbital approach for the prospective safety evaluation of chemicals (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

D F Lewis

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

C Ioannides

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

D V Parke

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

English

0 references

publication date

1 January 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

412

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

41-54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

Are animal tests relevant in cancer risk assessment? A persistent issue becomes uncomfortable

10 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Adjudicating cancer causation: scientific, political, and legal conflicts

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Molecular dimensions of the substrate binding site of cytochrome P-448

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Structural requirements for substrates of cytochromes P-450 and P-448

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Prediction of chemical carcinogenicity from molecular and electronic structures: a comparison of MINDO/3 and CNDO/2 molecular orbital methods

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Molecular orbital studies of oxygen activation and mechanisms of cytochromes P-450-mediated oxidative metabolism of xenobiotics

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Metabolic activation of carcinogens and toxic chemicals.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

The cytochromes P450 and mechanisms of chemical carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

On the significance of the cytochrome P-450-dependent hydroxyl radical-mediated oxygenation mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Role of free radicals and catalytic metal ions in human disease: an overview

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Role of reactive oxygen species in biological processes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Active Oxygen Species as Factors in Multistage Carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Validation of a novel molecular orbital approach (COMPACT) for the prospective safety evaluation of chemicals, by comparison with rodent carcinogenicity and Salmonella mutagenicity data evaluated by the U.S. NCI/NTP.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and rationalization of CYP2E substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Strategic approaches to drug design. I. An integrated software framework for molecular modelling.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Antimutagenicity of ellagic acid towards the food mutagen IQ: Investigation into possible mechanisms of action

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

The influence of chemical structure on the extent and sites of carcinogenesis for 522 rodent carcinogens and 55 different human carcinogen exposures

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

A retrospective evaluation of COMPACT predictions of the outcome of NTP rodent carcinogenicity testing

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Interaction of some peroxisome proliferators with the mouse liver peroxisome proliferator-activated receptor (PPAR): a molecular modelling and quantitative structure-activity relationship (QSAR) study

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Effects of acute and sub-chronic administration of iron nitrilotriacetate in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

A prospective toxicity evaluation (COMPACT) on 40 chemicals currently being tested by the National Toxicology Program

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

The use of computers in the safety evaluation of drugs and other chemicals.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

Mutagenesis and carcinogenesis: endogenous and exogenous factors

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900145-9

7 January 2021

10.1016/S1383-5718(97)00145-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9508363%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference