Downregulation of human polo-like kinase activity by antisense oligonucleotides induces growth inhibition in cancer cells (Q74355620)

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10 November 2019

title

Downregulation of human polo-like kinase activity by antisense oligonucleotides induces growth inhibition in cancer cells (English)

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10 November 2019

7

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10 November 2019

author name string

Birgit Spänkuch-Schmitt

1

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10 November 2019

Georg Wolf

2

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10 November 2019

Christine Solbach

3

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10 November 2019

Sibylle Loibl

4

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10 November 2019

Rainald Knecht

5

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10 November 2019

Manfred Stegmüller

6

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10 November 2019

Manfred Kaufmann

8

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10 November 2019

Klaus Strebhardt

9

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10 November 2019

language of work or name

English

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publication date

1 May 2002

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10 November 2019

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10 November 2019

volume

21

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10 November 2019

page(s)

3162-3171

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10 November 2019

issue

20

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205412

10 November 2019

exact match

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cites work

Antisense oligonucleotides: towards clinical trials

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7 January 2021

Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 to the EPH-related receptor human embryonal kinase 2 promotes tyrosine kinase activity

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7 January 2021

Duplication of Spindle Plaques and Integration of the Yeast Cell Cycle

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7 January 2021

Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila

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Vitravene--another piece in the mosaic

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7 January 2021

Potential roles of antisense technology in cancer chemotherapy

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A pharmacokinetic evaluation of 14C-labeled afovirsen sodium in patients with genital warts.

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PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

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7 January 2021

Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors

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7 January 2021

Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages

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7 January 2021

A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5

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7 January 2021

Antisense--time to shoot the messenger

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7 January 2021

Cell cycle- and terminal differentiation-associated regulation of the mouse mRNA encoding a conserved mitotic protein kinase

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7 January 2021

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes

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7 January 2021

Prk, a cytokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas

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7 January 2021

polo encodes a protein kinase homolog required for mitosis in Drosophila

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7 January 2021

Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo

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7 January 2021

On the Regulation and Function of Human Polo-like Kinase 1 (PLK1): Effects of Overexpression on Cell Cycle Progression

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7 January 2021

Phase I evaluation of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C-alpha, in patients with advanced cancer

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7 January 2021

The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells.

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7 January 2021

Identification of an early-growth-response gene encoding a novel putative protein kinase

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7 January 2021

Does antisense exist?

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7 January 2021

Prognostic value of pololike kinase expression in melanomas

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7 January 2021

Pathway specificity of reticulospinal and vestibulospinal projections in the 11-day chicken embryo.

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7 January 2021

The state of the art in antisense research

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7 January 2021

Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

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7 January 2021

Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer.

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7 January 2021

Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects

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7 January 2021